Neoplasia Of The Heart

Question 1

Types of cardiac tumors ranked from most common to least common

Answer 1

HSA > aortic body tumors (chemodectomas and paragangliomas)

HSA 40-69%
ABT 8-28%

Question 2

Breeds at risk for cardiac HSA

Answer 2

Goldens
GSDs
Boxers
Labs
Cockers

Question 3

Breeds at risk for aortic body tumors

Answer 3

Brachys - bulldogs, boxers, bostons
GSDs
Labs
Goldens

Question 4

What has been suggested to stimulate development of aortic body tumors in brachycephalic breeds

Answer 4

Chronic hypoxia

Question 5

CXR have what sensitivity for cardiac HSA

Answer 5

47% - they are insensitive for cardiac tumors

Question 6

What is the sensitivity and specificity of echo for detection of cardiac masses? Was it higher or lower for R atrial/auricular or heart base tumors?

Answer 6

Overall: sensitivity 82%, specificity 100%

Higher for R atrial/auricular

R atrial auricular: sensitivity 82%, specificity 99%
Heart base: sensitivity 74%, specificity 98%

Question 7

PPV and NPV for echo for detection of cardiac mass

Answer 7

PPV 100%
NPV 75%

Question 8

PPV and NPV for echo specifically for HSA

Answer 8

PPV 92%
NPV 64%

Question 9

What factors lead to false negative results

Answer 9

Tumor location - extrapericardial, non avatars pericardial, small auricular masses
Size

Question 10

Pericardial effusion occurs in what percent of dogs with cardiac HSA

Answer 10

82%

Question 11

How often is pericardial fluid cytology diagnostic

Answer 11

Very infrequently - 8%

Better if HCT <10%

Question 12

Prognosis for primary cardiac HSA

Answer 12

Poor

W/sx 16d-4m
W/sx + dog = 175d
W/dox alone = 116-140d

Question 13

Prognosis for aortic body tumors

Answer 13

With pericardectomy 661-760d (vs 42-129d without)

Question 14

Prognosis for cats

Answer 14

Poor - lymphoma 9d, but with CHOP one cat lived for 750d (probably an outlier)