neoplasms

Question 1

label these

Answer 1

Question 2

Whats the arrow pointing to and where is it located

Answer 2

ependymal cells in ventricles

Question 3

neurons are mitotically active in ____

Answer 3

children

Question 4

adult neoplasms aoften arise in the _____

Answer 4

supratentorium

Question 5

cells that adult tumors arise from

Answer 5

astrocytes and oligodendrocytes

Question 6

childhood neoplams often arise in the _____. give examples

Answer 6

• infratentorium
• might arise in pons, 4th ventricle, cerebellar regions

Question 7

tumor within the optic nerve is called

Answer 7

optic glioma

Question 8

tumor pathology is classified based on

Answer 8

biological agressiveness

Question 9

_______ is a term that denotes lesions that are within the brain parenchyma, in contrast to______, which describes lesions outside the brain

Answer 9

• intra-axial
• extra-axial

Question 10

intra axial examples

Answer 10

•Intra-axial: Gliomas, Embryonal neoplasms

Question 11

extra axial examples

Answer 11

•Extra-axial: Meningiomas, Peripheral nerve neoplasms

Question 12

location of Medulloblastoma

Answer 12

cerebellum

Question 13

growth pattern of Medulloblastoma

Answer 13

poorly differentiated but well circumscribed, solid mass that enhances without contrast

Question 14

What do we see here?

Answer 14

Homer wright rosettes in medulloblastoma

Question 15

locations for Pilocytic astrocytoma (WHO grade I)

Answer 15

Cerebellum

Hypothalamus

Optic nerve

Question 16

in MRI, contrast enhancement indicatinos disruption of normal ______

Answer 16

blood - brain barrier

Question 17

Answer 17

pilocytic astrocytoma

Question 18

common location for ependymoma

Answer 18

• Cerebellum
• Spinal cord

Question 19

Answer 19

perivascular rosettes characteristic of ependymoma

Question 20

ependymomas frequently seed the CSF and can form ______

Answer 20

drop metastases

Question 21

most common brain tumor in adults

Answer 21

meningioma

Question 22

most common glial cell tumor in adults

Answer 22

glioblastoma

Question 23

location of diffuse astrocytoma

Answer 23

cerebral hemisphere

Question 24

common location for glioblastoma

Answer 24

cerebral hemispheres

Question 25

Most common CNS tumor with female predominance

Answer 25

meningioma

Question 26

growth patterns of meningioma

Answer 26

Extra-axial mass Can invade bone Can invade brain

Question 27

imaging features of meningioma

Answer 27

Extra-axial mass Dural tails T1 hypointense Frequent calcifications Uniformly enhancing

Question 28

histologic features of meningioma

Answer 28

Minimal cytologic atypia Cellular whorls (A) Calcifications (B) •psammoma bodies

Question 29

10X more common than all primary CNS neoplasms combined

Answer 29

metastasis!

Question 30

CNS neoplasms present with:

Answer 30

* Generalized mass effects * Raised intracranial pressure * Hydrocephalus * Localizing signs and symptoms * Epilepsy (focal or generalized seizures) * Focal neurological deficits

Question 31

neoplasm composed of Schwann cells. Isolated at periphery of nerve.

Answer 31

schwannoma

Question 32

Composed of clones on non-myelinating Schwann cells. Infiltrates ***into*** nerve.

Answer 32

neurofibroma