Nerves Unit 4 Flashcards

(46 cards)

1
Q

What are the primary functions of the nervous system?

3 Functions

A

Receive Information
Process Information
Initiate Response

These functions involve receptors, integrators, and effectors.

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2
Q

What does the central nervous system (CNS) consist of?

A

Brain and spinal cord

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3
Q

What comprises the peripheral nervous system (PNS)?

A

Nerves and ganglia

Nerves are bundles of neuronal axons, while ganglia are collections of cell bodies.

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4
Q

What are the two functional divisions of the PNS?

A
  • Sensory (afferent) division
  • Motor (efferent) division

Sensory - receptors TO CNS
Motor - AWAY from CNS to effectors

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5
Q

What are the roles of the autonomic nervous system?

A

Controls effectors like cardiac muscle, smooth muscle, and glands

Somatic - skeletal muscle

It has sympathetic (fight-or-flight) and parasympathetic (rest-and-digest) divisions.

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6
Q

What are neurons?

A

Cells that respond to stimuli with electrical activity and release neurotransmitters

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7
Q

What are glial cells?

Neuroglia

A

Support cells of the nervous system

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8
Q

What is the function of oligodendrocytes?

Glial Cells in CNS

A

Form myelin sheaths in CNS and insulate action potentials

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9
Q

What do astrocytes provide?

Glial Cells in CNS

A

Blood-brain barrier (BBB)

They protect CNS from blood-borne proteins, toxins, and cells.

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10
Q

What is the role of ependymal cells?

Glial Cells in CNS

A

Line cavities and produce cerebrospinal fluid (CSF)

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11
Q

What do microglia do?

Glial Cells in CNS

A

Specialized phagocytic white blood cells that clean debris and pathogens

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12
Q

What is the structure of a neuron?

A
  • Cell body (soma)
  • dendrites (branch extensions)
  • axon (nerve fiber)
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13
Q

What is the function of the myelin sheath?

Produced by oligodendrocytes (CNS) or schwann cells (PNS)

A

Insulates the axon

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14
Q

What are the characteristics of neurons?

5 Characteristics

A
  • Excitability
  • Conductivity
  • Secretion
  • Amitotic
  • Longevity
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15
Q

What are the three functional types of neurons?

What kinds of neurons are there?

A
  • Sensory (afferent) neurons
  • Interneurons (association)
  • Motor (efferent) neurons

Afferent - coming in
Association - in-between

Efferent - Going Out

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16
Q

What are the 3 structural types of neurons?

A
  • Multipolar - many dendrites, one axon, most common
  • Bipolar - one dendrite, one axon
  • Unipolar - no dendrites, one axon

Info moves in one direction

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17
Q

What is the resting membrane potential of neurons?

A

~ -70 mV

K (negative) concentrated inside

Na (positive) concentrated outside

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18
Q

What causes depolarization in neurons?

A

Na+ influx

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19
Q

What is hyperpolarization?

A

When the membrane potential becomes more negative than the resting potential

20
Q

What is an action potential?

A

A brief reversal in the charge on the membrane that occurs at the trigger zone

21
Q

What is the all-or-none rule in action potentials?

A

If ~-55mV, nothing happens
Once past ~-55mV, an action potential goes to completion and cannot be stopped

22
Q

What are the phases of an action potential?

A
  • Depolarization (positive, Na gates open and enter cell)
  • Repolarization (negative, Na gates close, K gates open, K enters cell)
  • Hyperpolarization
23
Q

What is the refractory period?

A

Period of resistance to stimulation where no new action potential can be triggered

Absolute (no go) and Relative (very hard to go again)

24
Q

What is saltatory conduction?

Myelinated Axons

A

Action potentials jump from node to node in myelinated axons, speeding up conduction

Na+ diffusion between nodes

25
What is a synapse?
Connection between a neuron and its target (synaptic cleft) | Targets: Neuron, Muscle, or Gland
26
What happens during neurotransmitter release?
Ca2+ enters, causing synaptic vesicles to fuse w/the membrane
27
What are excitatory postsynaptic potentials (EPSPs)?
Cell is more likely to fire (depolarize) due to Na+ influx
28
What are inhibitory postsynaptic potentials (IPSPs)?
Postsynaptic cell is less likely to fire (hyperpolarize) due to Cl- influx or K+ efflux
29
What is temporal summation?
Occurs when a single synapse receives many signals in a short period of time
30
What is convergence and divergence in neural signaling?
Convergence - Many inputs to one cell leading to integration Divergence - one cell passes info to many cells
31
What is multiple sclerosis?
Autoimmune disease causing **demyelination** | Risk groups - Ages 20-40, more women than men ## Footnote Symptoms - trouble w/muscle coordination and numbness, vision, memory
32
What is ALS (Amyotrophic Lateral Sclerosis)?
Rapidly progressing disease that kills the motor neurons | Risk groups - men over 40 ## Footnote Symptoms - loss of muscle control
33
What is cerebral palsy (CP)?
Congenital disorder affecting muscle movement control | Risk groups - age 3 and older ## Footnote Symptoms - lack of muscle control
34
What is spina bifida?
Neural tube defect affecting spinal cord development during the first trimester | Risk groups - Obese and diabetic pregnant women ## Footnote Symptoms - paralysis in legs, bladder control issues
35
What are Schwann Cells? | Glial Cells in PNS
Make myeline sheath in PNS and insulate action potentials Each axon has several Schwann cells | One axon per Schwann cell
36
What are Satellite Cells? | Glial Cells in PNS ## Footnote Similar Function to Astrocytes
Surround neuron cell bodies Barrier cells
37
What are Nodes of Ranvier?
Gaps in the myelin sheath where axon is exposed | Allows for saltatory conduction
38
What is Myelin Sheath?
Insulating layer around an axon
39
What are insulators?
Substances w/high resistance | Myelin sheath
40
What are conductors?
Substances w/low resistance | Cytoplasm
41
What is repolarization?
Going from postive to negative, towards the resting potential
42
What is a graded potential?
A potential that varies in magnitude
43
What is a decremental potential?
Potential that gets weaker the farther they spread
44
What is the Na+ to K+ ratio when returning to the resting potential?
3Na+ / 2K+
45
What is Spatial Summation?
Occurs when single synapse receives signals from many presynaptic cells
46
What is Fibromyalgia?
Disorder causing muscle pain | Risk groups - middle aged women ## Footnote Symptoms - tender skin, headaches, sleep disorder, memory issues, numbness of hands and feet