Nervous system and embryology Flashcards

week 1 (68 cards)

1
Q

Differentiate between visceral and somatic nerve fibres

A

Visceral

messages from organs, viscera of thoracic and abdominal cavities

Somatic

Impulses from outside body or via movements of muscles and joints

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2
Q

What are the 4 main regions of the brain?

A

Cerebrum
Cerebellum
Diencephalon
Brain Stem

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3
Q

How many lobes does the cerebrum have and what are their functions?

A

Frontal: voluntary motor movement, verbal communication and cognitive skills.

Temporal: Hearing, smell, emotion

Parietal: Conscious awareness of sensations. Somatic sensation and integration.

Occipital: Visual awareness and processing

Insula: pain and visceral sensation. Taste and memory.

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4
Q

What are the functions of the cerebellum?

A

Motor learning

Equilibrium and posture

Smoothens movements

Receives proprioceptive information

Coordinates body position.

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5
Q

What is the general function of the Diencephalon and the functions of its two components?

A

General function

Relay info from cerebrum to other functional centers

Two components

Hypothalamus: homeostasis

Thalamus: relay station for sensory impulses

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6
Q

What are the general functions of the Brainstem

A

bidirectional passageway for tracts between the cerebellum and spinal cord

autonomic and reflex centres required for survival

origins of cranial nerves

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7
Q

What are the three components of the brainstem and their functions?

A

Pons: ascending and descending info,

Medulla Oblongata: Autonomic and respiratory

Midbrain: visual and audio

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8
Q

What are the respective gyrus for the Motor and Sensory Homunculus?

A

Motor= Pre-central gyrus (primary cortex)

Sensory= postcentral gyrus (somatosensory cortex)

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9
Q

Aspects of Spinal cord structure

A

31 pairs

Motor and sensory

Forms plexuses (web of nerves)

Exit via interverbal foramen

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10
Q

3 sets of plexuses

A

Cervical, Brachial

Lumbar, Saccral

Mixed roots

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11
Q

What are the three horns of Grey Matter in the Spinal cord?

A

Dorsal horn
-somatic sensory axons and interneuron cell bodies
-visceral sensory axons and interneuron cell bodies

Lateral horn
-autonomic motor cell bodies (T1-L2)

Ventral horn
-somatic motor cell bodies

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12
Q

How many pairs of cranial nerves are there?

A

12

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13
Q

What is neurulation?

A

Neural plate bends up and then fuses to from hollow tube.

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14
Q

What is a somite?

A

Transient units that gives rise to repetitive structures including vertebrae, ribs and skeletal muscles.

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15
Q

What is a Sclerotome?

A

Part of a somite that gives rise to a bone or skeletal tissue

Forms vertebral cartilage

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16
Q

What is a Dermatome?

A

Forms back of dermis

Area of skin receiving sensory innervation from single spinal nerves dorsal root.

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17
Q

What is myotome?

A

Group of muscles innervated by single spinal nerve root.

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18
Q

Briefly outline embryological development of musculoskeletal system

A

1- Notochord forms mesoderm cells after gastrulation

2- signals from notochord cause inward folding of ectoderm at neural plate

3- end of neural plate fuses and disconnects to form a neural tube

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19
Q

Which germ layer does the nervous system develop from

A

Ectoderm

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20
Q

What embryonic structure do vertebrae develop from

A

sclerotome

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21
Q

What structure of the spinal cord anchors it securely to the coccyx?

A

The filum terminale

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22
Q

What type of fibers do the posterior (dorsal) roots contain?

A

afferent fibers

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23
Q

Trigeminal nerve

A

largest
arises from pons
sensory innervation of the face

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24
Q

Facial nerve

A

motor innervation of facial expression

pons and medulla

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25
vagus nerve
main parasympathetic nerve from medulla
26
Spinal accessory nerve
motor innervation of two neck muscles from C1-5/6 and medulla
27
Hypoglossal
Motor innervation of tongue from medial aspect of medulla
28
What are the four main plexuses of the body?
cervical, Brachial, Lumbar and Sacral
29
what is the function of the primary motor cortexes?
encodes the direction of movement
30
what is the function of the primary somatosensory cortexes?
processing afferent somatosensory input and contributes to the integration of sensory and motor signals necessary for skilled movement.
31
Which tract carries impulses between the left and right hemispheres of the brain?
thick tract of nerves called the corpus callosum at the base of the groove.
32
where are white and grey matter located in the spinal cord
grey = interior white = surrounds
33
what type of fibres carry afferent information in the spinal cord?
Dorsal root
34
what type of fibres carry efferent information in the spinal cord?
Ventral root
35
Dorsal
on or relating to the upper side or back of an animal, plant, or organ.
36
ventral
of or relating to the belly : abdominal. being or located near, on, or toward the lower surface of an animal
37
posterior
near the rear or end further back in position
38
anterior
in front of
39
proximal
nearer to the center
40
distal
away from the centre
41
what is the purpose of the cervical and lumbar enlargements along spinal cord
accomadate for the greater number of nerves and connections necessary to process info from uperr and lower limbs
42
Moving from brain to coccogeal, what is the order of spinal regions?
Cervical (C1-7) Thoracic (T1-12) Lumbar (L1-L5) Sacral (S1-5)
43
conus medullaris
distal end of the spinal cord
44
what are the start and end points of the spinal cord?
1. continuous with the brainstem at the level of the foramen magnum 2. tapers at the conus medullari (continues as the cauda equina) at the level of L1/L2)
45
what anchors the spinal to the coccyx?
filum terminale
46
what are the 3 horns of spinal cord grey matter?
dorsal horn lateral horn ventral horn
47
What are the neuron types of the three horns of the spinal cord grey matter?
dorsal - somatic and visceral sensory axons - interneuron cell bodies lateral (only sympathetic) -autonomic motor neuron cell bodies ventral horn somatic motor neuron cell bodies
48
moving from top to bottom, what are the names of the 5 branches of brachial plexuses?
musculocutaneous axillary radial median ulnar
49
what (from top to bottom) are the cords that lead into the branches (plexuses)?
lateral --> musculocutaneous and median posterior --> axillary and radial medial --> median and ulnar
50
What are the 4 main plexuses and their spinal roots?
cervical -C1-C4 Bracial - C5-C8, T1 -musculocutaneous -axillary -radial -median -ulnar Lumbar T12-L4 Sacral -L4-S4
51
Where are sensory neuron cell bodies located?
within sensory ganglia which may be in the dorsal root of the spinal cord or along cranial nerves.
52
what is the cauda equina?
a group of axons acting as a continuation of the spinal cord, translates to ‘horsetail’
53
How are spinal nerves created?
union of the dorsal root (from dorsal rootles) and the ventral root (from ventral rootlets)
54
What does dorsal roots and rootlets contain?
Dorsal rootlets: somatic and viscera; sensory neuron axons Dorsal root: sensory neuron axons and ganglion
55
What does ventral rootlets contain?
somatic and autonomic motor neurons
56
What foramen do spinal nerves exit from?
interverebrael foramen
57
proprioception
Awareness of position that requires sensory input from cerebral cortex and cerebellum and motor control.
58
what are the different types of muscle morphology?
Pennate: Fusiform Parallel Convergent Circular
59
What is fusiform and an example.
thick muscle belly that tapers on both sides (bicep brachii)
60
Gastrulation
Bilaminar embryonic disc --> trilaminar embryonic disc
61
what does the ectoderm develop into?
Develops into epidermis, epidermal derivatives (hair/ nails) and nervous system.
62
What are the three strcutures of the mesoderm and what do they develop into?
3 structures that develop into various parts Notochord: axial skeleton Paraxial mesoderm: develops into somite forming axial skeleton, muscle, dermis and most CT Head mesenchyme: CT and musculature of fact
63
What occurs GENERALLY in first 8 weeks of muscle embryo development?
Gastrulation (halfway wk 2) Folding of embryonic disc (wk 3) Neurulation (early wk 4) Limb development (week 4—8)
64
MSS embryological development step 1 (gasturlation)
transformation from a bilaminar to trilaminar embryonic disc
65
MSS embryological development 2- folding of the embryonic disc
(week 3) - rapid growth of head and tail causes the folding of the embryonic disc into a tube
66
MSS embryological development 3- neurulation
(early week 4) - the notochord stimulates the neural plate to transform into the neural tube - somites develop and align on either side of the neural tube -
67
MSS embryological development 4- limb development
- limb buds, containing a ventral and dorsal muscle mass, form at week 4 (UL before LL) - rotation of the limbs at weeks 7-8 - UL laterally, moving the elbow posterior - LL medially, moving the knee anterior
68
during neurulation, what does sclertome, dermatome and myoterm become?
sclerotome → vertebrae - myotome → muscle - dermatome → dermis