Neuro Flashcards
(230 cards)
Treatment of CVA
If CT shows ischaemia
Thrombolysis within 4.5 hours
Thrombectomy if within 6 hours with thrombolysis for proximal anterior circulation demonstrated by CTA
If unable to- aspirin 300mg for 2 weeks
If thrombolysis given- aspirin 24 hours after repeat CT
Ix for SAH
CT head- non contrast
>12 hrs later- LP for xanthochromia
CI to thrombylysis
ABC SHIP
Bleeding- GI bleed in 3 weeks, LP in 7 days
Coagulation problems
Stroke <3 months
Uncontrolled Hypertension- >200
Intracranial neoplasm
Pregnancy
Scoring systems of stroke
NIHSS- quantifies severity
ROSIER- differentiate between strokes and mimics
Mx of TIA
Aspirin 300mg
Unless taking warfarin, DOAC, bleeding disorder- CT head
Or >7d since sx
When to give carotid endarterectomy
When occlusion is >70%
What is total anterior circulation infarct and its symptoms
Middle and anterior cerebral
Unilateral hemiparesis +/- hemisensory
Homonymous hemianopia
Cognitive dysfunction
Posterior inferior cerebellar infarct symptoms
Lateral medullary syndrome Loss of pain and temp ipsilateral face, loss on contralateral limbs
Ataxia, nystagmus
Can get difficulty swallowing
Anterior inferior cerebellar infarcts
Loss of pain and temp ipsilateral face, loss on contralateral limbs
Ipsilateral paralysis and deafness - hearing is AICA over PICA
Ataxia, nystagmus
Can get difficulty swallowing
Vestibular schwannoma symptoms
Vertigo, hearing loss, tinnitus
Absent corneal reflex
Associated with NFM 2
Canvernous sinus thrombosis affects
Cranial nerves V1+2
3+4+6
What Ix for MG
Tenilson test
AchR AB
CXR- thymic hyperplasia
What can cause normal pressure hydrocephalus
SAH
Meningitis
Trauma
Types of focal seizures and symptoms
Aware and unaware or evolving into generalised typically tonic clonic
Temporal-hallucinations, lip smacking
Frontal- head movements
Occipital- floaters
Parietal- parasthesia
Symptoms of GBS
Ascending weakness LMN
After GE or STI
Secondary prevention of CVA
Clopidogrel 75mg
Tx of SAH
Coiling
Parkinsonism vs parkinsons
Parkinsonism- symmetrical, rapid, poor response to levadopa
Parkinsons- asymmetrical, progressive, good response
Parksonism
A group of neurological disorders that cause movement problems similar to those seen in Parkinson’s disease such as tremors, slow movement and stiffnes
Parkinson plus syndromes
MSA- autonomic dysfunction- postural hypotension, cerebellar ataxia- falls, ED
Vertical gaze palsy- postural instability falls, speech, dementia
CBD- unilateral parks, aphasia, alien limb
Dementia with LB- hallucinations
Tx of Parkinson’s
Levadopa with dopa decarboxylase
Co-careldopa
Tx of epilepsy
Tonic clonic- valproate, females- lamotrigine or leve
Absence-Ethosuximide
Myoclonic- valproate, female- leve
Tonic/atonic- valproate, female- lamo
Focal- lamo/leve
SE management
ABC
Pre-hospital- PR diazepam/buccal midazolam, hospital IV lorazepam
Second dose after 10-20 mins then phenytoin then ICU after 45 mins
CT head immediately guidelines
FFS
GCS <13
Vomit >1
Fracture of skull
Focal neurological deficit
Seizure