NEURO 129 Spinal Cord Compression Flashcards

(35 cards)

1
Q

Through what structure does the sensory input enter the spinal cord?

A

Dorsal root

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2
Q

Through what structure does the efferent response leave the spinal cord?

A

Ventral root

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3
Q

What are three musculoskeletal sensory receptors?

A

Muscle spindles, Golgi tendon organ and joint receptors

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4
Q

What does the muscle spindle detect?

A

Stretch in the muscle

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5
Q

How is the muscle spindle kept under tension and why?

A

by gamma motor fibres which keep it tense as without tension it would be unable to detect any changes in stretch

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6
Q

What is the purpose of the golgi tendon organ?

A

To provide inhibitory feedback “inverse myotatic reflex”

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7
Q

What activates the golgi tendon organ and what is the response?

A

Prolonged contraction or stretch producing muscle inhibition - prevents tendon damage

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8
Q

Describe the basic spinal reflex - the knee jerk reaction

A

Tapping patellar ligament, stretches quadriceps muscle, activates 1a afferent nerve –> synapses with alpha motor neurone = subsequent muscle contraction
This has an excitatory synapse with an inhibitory interneurone which inhibits the alpha motor neurone causing muscle relaxation

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9
Q

What are Renshaw cells?

A

Inhibitory interneurones

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10
Q

What do Renshaw cells do?

A

Release glycine back onto the alpha motor neurone to inhibit it

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11
Q

Where do instructions for voluntary movement lie in the brain?

A

In the motor cortex - the motor homonculus

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12
Q

What is most of the motor homonculus devoted to?

A

Hands, face and tongue

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13
Q

What is the main descending motor pathway in the CNS?

A

The corticospinal tract

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14
Q

Where does the corticospinal tract originate?

A

Pyramidal cells of the motor cortex

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15
Q

Where does the corticospinal tract cross over?

A

The pyramids of the medulla

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16
Q

What are the 4 other areas, besides the motor cortex, that the corticospinal tract arises from?

A

Primary somatosensory receiving area, premotor cortex, supplementary area and posterior parietal cortex

17
Q

What is apraxia?

A

An inability to produce a specific motor act even though sensory and motor pathways remain intact

18
Q

What are the two main ascending tracts to the CNS?

A

Spinothalamic and the Dorsal Columns

19
Q

What does the spinothalamic tract carry sensory information about?

A

Pain, tempterature, touch and pressure

20
Q

What does the dorsal column carry sensory information about?

A

Joint position and fine discriminatory touch

21
Q

Where does the spinothalamic tract deccusate?

A

At the level it enters the spinal cord

22
Q

Where do the dorsal columns decussate?

A

In the medulla

23
Q

What are the main signs of an UMN lesion?

A

Paralysis/weakness of movement of affected muscles
HyPERreflexia
HyPERtonia

24
Q

Why is there Hypertonia/reflexia in an UMN lesion?

A

Due to lack of inhibition

25
What are the main signs of a LMN lesion?
HyPOreflexia Fasiculations HyPOtonia Muscle atrophy and denervation
26
What is Cauda Equina Syndrome due to?
Compression of the lumbar and sacral nerve roots within the cauda equina
27
What is motor neurone disease due to?
Disease of the anterior horn cells of the spinal cord
28
What is Myasthesia gravis?
Acquired autoimmune disease against the acetylcholine receptor at the NMJ
29
What is the main the clinical feature of myasthesia gravis?
Muscle weakness and fatiguability
30
What is a muscular dystrophy and give an example
Inherited disorder of muscle e.g. Duchennes
31
What happens in muscular dystrophy?
There is progressive muscle wasting and weakness with proximal muscles being affected worse than distal ones
32
What is a radiculopathy?
A Nerve root compression
33
What is Brown-Sequard syndrome?
A lesion in one half of the spinal cord - hemisection | from trauma or disc hernia or compressive tumour
34
What is a syringomelia
Expanded central canal in cervical region
35
In UMN lesion what is pyramidal weakness?
Where the flexors of the lower limb and extensors of the upper limb are stronger than the opposite