Neuro

Question 1

Generalized convulsive status epilepticus is generalized tonic clonic seizure lasting more than 5 min or two gtcs occurring within 5 minutes of each other without a return to baseline mental status

Question 2

Psychogenic non epileptic spells often related to ptsd and conversion disorder which has
Asynchronous flailing of variable limbs
Side to side head shaking
Pelvic thrusting
Prolonged duration > 5min or even hours

Question 3

Idiopathic intracranial hypertension has been associated with kidney failure, endocrine disorder, tetracycline, retinoic acid, progresterone or estrogen supplements

Question 4

Treat idiopathic intracranial hypertension

Answer 4

Acetazolamide
Topiramate

Question 5

Amitriptyline is the only agent that has been shown to be effective in the prevention of tension type headache

Question 6

Onabotulinum toxin a use for

Answer 6

Chronic migraine

Question 7

First line preventive treatment for episodic migraine < 15 days month and chronic migraine > 15 days month

Question 8

Dexamethasone can be used in craniotomy case by case to reduce surgery related edema

Question 9

In reversible cerebral vasoconstriction syndrome, a rare condition that can be triggered by medications, such as amphetamine or ssri, verapamil can reduce neurologic adverse events

Question 10

Creutzfeldt jakob disease diagnosed by real time quaking induce conversion assay in the csf
14-3-3 protein and tau protein also increase but non sensitive and specificity

Question 11

In alzheimer disease, decrease csf Abeta 42 and increase tau and phosphorylate tau level are highly specific

Question 12

Inotersen and patisiran is approved for hereditary amyloid neuropathy

Question 13

Anti muscle specific kinase antibody use for a variant of myasthenia gravis

Question 14

Serum GQ1b antibody is specific for the miller fisher variant of guillain barre syndrome

Question 15

Pompe disease test
Acid maltase activity in leukocyte and genetic testing for the alpha glucosidase gene

Question 16

Treatment of fatigue is modafinil

Question 17

Amyloid specific pet scan uses 18 F flurodeoxyglucose to detect amyloid plaques to differentiate frontal temporal dementia from alzheimer disease

Question 18

Treat gait dysfunction in multiple sclerosis is dalfampridine

Question 19

multiple sclerosis spasticity treat by tizanidine, baclofen, cyclobenzaprine and benzo

Question 20

Treat attack of cluster headache

Answer 20

Subcu sumatriptan and 100% oxygen

Question 21

Treat trigeminal neuralgia

Answer 21

Carbamazepine

Question 22

Headache treat by indomethacine
Chronic paroxysmal hemicrania
Hemicrania continua
Primary cough headache

Question 23

Thrombectomy in ischemic stroke should be within 6 hours

Question 24

Anticoagulation should be held 24 hours after intravenous thrombolysis

Question 25

Bo goal following thrombolytic therapy is

Answer 25

180/105

Question 26

Treat bp on ischemic stroke ineligible for thrombolytic therapy when bp higher than

Answer 26

220/120

Question 27

Muscle mounding after percussion is myoedema, happen in hypothyroid myopathy

Question 28

Poly myalgia rheumatica will have increased esr and crp but normal ck

Question 29

Fibromyalgia with normal esr crp and ck

Question 30

Risk for rupture is low if arterial aneurysm less than 7mm in posterior circulation and less than 12 mm in anterior circulation

Question 31

Base on Mini Mental State Examination Score 20-23 mild dementia Score 10-19 moderate dementia Score less than 10 severe dementia Mild to moderate treat with donepezil, rivastigmine, galantamine Moderate to sever: add memantine as an adjunctive

Question 32

Ocp will not increase stroke risk in migraine without aura

Question 33

Treat behavioral variant frontotemporal dementia by ssri

Question 34

Treat dementia with lewy bodies by

Answer 34

Rivastigmine

Question 35

Treat rapid eye movement sleep behavior disorder in dementia with lewy bodies

Answer 35

Clonazepam

Question 36

If treat dementia with lewy bodies by antipsychotic drug, behavioral problem will be more

Question 37

Levetiracetam can worsen depression anxiety suicidal ideation Zonisamide also cause psychiatric and behavioral side effect

Question 38

Carbamazepine clobazam gabapentin lamotrigine oxcarbazepine phenytoin valproic acid can decrease the risk of psychiatric and behavioral side effect

Question 39

Amantadine is an NMDA receptor antagonist used to treat levodopa induced dyskinesia

Question 40

Deep brain stimulation is used for experienced moto fluctuations or have a refractory tremor

Question 41

Treatment for end-of-dose weaning off phenomenon include Increase levodopa Add catechol O methyltransferase inhibitor like entacapone Add dopamine agonist like ronipirole Add monoamine oxidase type B inhibitor like selegiline

Question 42

Differentiate MS and neuromyelitis optica NMO bilateral optic neuritis, longitudinal extensive myelitis, csf mostly neutrophils MS unilateral optic neuritis, segmental myelitis

Question 43

Neuromyelitis optica test is aquaporin 4 antibody

Question 44

The cerebella tonsillar descent in the presence of dural thickening and enhancement suggest intracranial hypotension

Question 45

Ocrelizumab is a disease modifying therapy for long term management of MS

Question 46

Pharmacologic prevention of episodic migraine Level A Propranolol timolol metoprolol Valproate topiramate Candesartan Level B Amitriptyline atenolol venlafaxine

Question 47

Biologic therapy in migraine

Answer 47

Rimegepant episodic Atogepant episodic and chronic Erenumab Frenamezumab Eptinezumab Galcanezumab All these for episodic and chronic

Question 48

Onabotulinum toxin a use for chronic migraine, not episodic

Question 49

Verapamil can be used to prevent of episodic cluster headache

Question 50

Antiepileptic medications in pregnancy Lamotrigine can worsen myoclonic seizure in some patients Levetiracetam Oxcarbazepine

Question 51

Gabapentin use to treat focal seizure, not generalized seizure

Question 52

Topiramate can cause cleft lip and cleft palate in offspring

Question 53

Valproic acid can cause weight gain, pcos, teratogenicity on women

Question 54

Bo should be lower 185/100 before alteplase and lower 180/105 after ateplase

Question 55

Lamotrigine gabapentin and levetiracetam are better use in older adult

Question 56

Oxcarbazepine carbamazepine and eslicarbazepine can cause hyponatremia due to siadh

Question 57

Treat essential tremor Propanolol Primidone Topiramate Second line Clonazepam Deep brain stimulation Focused ultrasound thalamotomy

Question 58

Topiramate is contraindicated in kidney stone

Question 59

Aspirin should be held for 24 hours after thrombolysis to reduce intracerebral hemorrhage

Question 60

Patient with asymptomatic carotid artery stenosis less than 80% have a low annual risk for stroke. Just intervene if stenosis more than 70%

Question 61

In intracranial hemorrhage and sbp more than 150, acute lowering of sbp to 140 mmHg is safe and effective

Question 62

Iv nitroprusside can increase intracranial pressure

Question 63

Diagnose vascular dementia base on lack of hippocampal atrophy and presence of confluent white matter hyperintensities on MRI

Question 64

In MS, Uhthoff phenomenon in which chronic neurologic symptoms become more prominent in the setting of fever

Question 65

Tics can be suppressible