Flashcards in Neurobio of addiction Deck (8)
What is tolerance to reward?
Due to repeated dopamine release, dopamine receptors down regulate
Threshold for rewards during abstinence is increased
Normal pleasure experiences don't evoke adequate reward response
These persist despite prolonged abstinence.
What is the orbito frontal cortex?
Key creator of motivation to act
Addicts have increased activation of OFC when presented with drug cues.
Role of the pre frontal cortex?
Helps intention guide behaviour
Modulates powerful effects of the reward pathway
What is the function of the striatum and hippocampus?
Striatum- Habit learning
Hippocampus- Declarative learning
Which brain areas are responsible for inhibitory control?
Prefrontal cortex and Anterior cingulate gyrus
Which brain areas are responsible for motivation/drive?
Which brain area is responsible for memory/learning?