Neurons Flashcards

1
Q

where do APs propagate from on a neuron

A

axon hillock

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2
Q

what stain stains myelin

A

luxor fast blue

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3
Q

what stain stains Nissl (RER)

A

cresol violet

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4
Q

what colour does eosin stain proteins

A

red

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5
Q

what colour does haemotoxylin stain nucleic acids

A

blue

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6
Q

what are the 3 functional classes of neurons

A

afferent
efferent
interneurons

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7
Q

Where are interneurons

A

found within CNS

lie entirely within CNS

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8
Q

what do afferent neurons do

A

convey info from tissues/ organs to CNS; sensory receptors on peripheral ends so respond to physical/ chemical changes in environment by generating signals in the neuron

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9
Q

what do efferent neurons do

A

convey info away from CNS to effector cells

have cell bodies/ dendrites within CNS

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10
Q

what do interneurons do

A

connect neurons within CNS

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11
Q

what is the composition of myelin

A

70& lipid
30% protein
highly compacted
20-200 layers of modified plasma protein wrapped around axon by nearby surrporting cells

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12
Q

where are oligodendrocytes found

A

CNS

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13
Q

where are Schwann cells found

A

PNS

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14
Q

what are nodes of Ranvier

A

where plasma membrane of axon is exposed to extracellular fluid

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15
Q

where are myelinated axons mainly found

A

somatic nerves i.e. fast sensory/ motor systems

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16
Q

where are unmyelinated axons mainly found

A

post-ganglionic autonomic fibres, fine sensory fibres, olfactory neurons and interneurons

17
Q

what is the difference in thickness between myelinated and unmyelinated axons

A

myelinated are thicker

18
Q

what are the 5 types of glial cells

A
oligodendrocytes
schwann cells
astrocytes
microglia 
ependymal cells
19
Q

describe oligodendrocytes

A

glial cells of CNS
myelinating cells that myelinate multiple axons
Provide metabolic support for axons

20
Q

describe Schwann cells

A

glial/ myelinating cells of CNS

myelinate single axons

21
Q

what are the differences between oligodendrocytes and Schwann cells

A

CNS v PNS

myelinate multiple axons v single axons

22
Q

what is the name of astrocytes in grey matter

A

protoplasmic

23
Q

what is the name of astrocytes in white matter

24
Q

where are protoplasmic astrocytes found

A

grey matter

25
where are fibrous astrocytes found
white matter
26
what are 3 types of astrocytes
radial glia muller glia Bergmann glia
27
what do astrocytes do
regulate ECF composition in CNS stimulate formation of tight junctions between cells in CNS capillary walls foot processes closely applied to capillaries sustain neurons metabolically
28
how do astrocytes regulate composition of ECF in CNS
remove K+/ neurotransmitters | take up glutamate and convert it to glutamine that can then be taken up by neurons and converted to glutamate
29
where are radial glia found
guide developing neurons - not found in adult brain
30
what are muller glia
specialised radial glia in retina
31
here are Bergmann glia found
cerebellum
32
describe microglia
``` specialised macrophage like cells phagocytic immune function in CNS migrate to site of damage contribute to synaptic plasticity ```
33
describe ependymal cells
line ventricles regulate production/ flow of CSF have cilia, microvilli and desmosomes barrier between CSF and brain