nicotine and caffeine Flashcards
(12 cards)
nicotine
main psychoactive component of tobacco
secondhand smoke
Smoke exhaled from a smoker or smoke released from a burning tobacco product
thirdhand smoke
Remnants from tobacco smoking gathered on material in the smoker’s local environment after smoking has finished
first uses of tobacco
in peru to enter trancelike state
what is the greatest cause of death from smoking
lung cancer
flue curing
venting heat through a metal flue onto tobacco leaves making smoke less harsh to inhale (neutralizes pH)
tar
particles released from burning tobacco
most effective routes of nicotine admin
inhaled/ e-liquid vapour
cotinine
active metabolite of nicotine
nicotine mech of action
agonist for cholinergic receptors
- cotinine is weak agonist
- receptor enters desensitized state after activation
- functional antagonist because receptors stay closed longer than open
- increase dopamine levels in nucleus accumbens
caffeine
member of xanthine chem class
- antagonist for adenosine receptors
caffeine + alcohol
increases risk of alcohol poisoning since caffeine reduces intoxicating effects