Flashcards in Non-melanom skin cancer Deck (9)
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1
Leser-trelat sign
Sudden eruption of many seborrhoeic keratoses
(malignant acanthosis nigricans)
2
Type of cyst seen in seborrhoeic keratosis?
Horn cysts can be seen in seborrhoeic keratosis
3
Squamous cell carcinoma precursors
Bowens disease (red patches, more often females, especially legs)
Actinic keratosis (from sun)
Viral lesions (especially ano-genital skin)
4
Erythroplasia of Queryat - what is this and what is it associated with?
Penile Bowen's
Associated with HPV
5
Chronic lupus vulgaris can give rise to which type of cancer?
Squamous carcinoma of the skin
6
Commonest clinical setting of squamous carcinoma of the skin and other associations?
COMMONEST CLINICAL SETTING:
elderly, sun exposed sites (face, ears, dorsal hands)
UV implicated
OCCASIONALLY ARISES:
chronic leg ulcers e.g. stasis ulcers
sites of burns; sinuses e.g chronic osteomyelitis
chronic lupus vulgaris
RARE ASSOCIATIONS:
xeroderma pigmentosum; dystrophic variant epidermolysis bullosa
7
Specific sites of squamous cell carcinoma that have a poorer prognosis?
Ear, nose, scalp
8
Primary small cell neuroendocrine carcinoma of the skin
Merkel cell carcinoma
9