Structure and Function

Question 1

Basal cell layer

Answer 1

Usually one cell thick
Small cuboidal
Lots of intermediate filaments (keratin)
Highly metabolically active

Question 2

Prickle cell layer

Answer 2

Larger polyhedral cells
Lots of desmosomes (connections)
Intermediate filaments connect to desmosomes

Question 3

KGPBD

Answer 3

Keratin layer
Granular layer
Prickle cell layer
Basal layer
Dermis

Question 4

Which layer would you find keratohylin granules (contain structural filaggrin & involucrin proteins) and odland bodies (lamellar bodies)?

Answer 4

Granular layer :)

think about it, they sound like granules!

Question 5

Origin of ‘cornified envelope’

Answer 5

Granular layer

Question 6

Cell nuclei are lost by this layer?

Answer 6

Granular layer

Question 7

Corneocytes: overlapping non-nucleated cell remnants
Insoluble cornified envelope
80% keratin & filaggrin
Lamellar granules release lipid
Tight waterproof barrier

Answer 7

Keratin layer

Question 8

Which layer would you find corneocytes?

Answer 8

Keratin layer