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Dermatology > Structure and Function > Flashcards

Flashcards in Structure and Function Deck (8)
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1

Basal cell layer

Usually one cell thick
Small cuboidal
Lots of intermediate filaments (keratin)
Highly metabolically active

2

Prickle cell layer

Larger polyhedral cells
Lots of desmosomes (connections)
Intermediate filaments connect to desmosomes

3

KGPBD

Keratin layer
Granular layer
Prickle cell layer
Basal layer
Dermis

4

Which layer would you find keratohylin granules (contain structural filaggrin & involucrin proteins) and odland bodies (lamellar bodies)?

Granular layer :)
(think about it, they sound like granules!)

5

Origin of 'cornified envelope'

Granular layer

6

Cell nuclei are lost by this layer?

Granular layer

7

Corneocytes: overlapping non-nucleated cell remnants
Insoluble cornified envelope
80% keratin & filaggrin
Lamellar granules release lipid
Tight waterproof barrier

Keratin layer

8

Which layer would you find corneocytes?

Keratin layer