NSAIDS

Question 1

What are the 5 NSAIDS drugs to know?

Answer 1

Aspirin, Ibuprofen, Naproxen, Celecoxib, Etoricoxib

Question 2

What type of NSAID is Aspirin?

Answer 2

Non-selective Irreversible COX inhibitors

Question 3

What type of NSAID is Ibuprofen & Naproxen?

Answer 3

Non-selective Reversible COX inhibitors

Question 4

What type of NSAID is Celecoxib?

Answer 4

Selective COX2 inhibitors

Question 5

What is the most dangerous contraindication of all NSAIDs?

Answer 5

Premature closure of ductus arteriosus (fetal lung bypass) hence AVOID IN 3RD TRIMESTER OF PREGNANCY

Question 6

What are the characteristics of Aspirin?

Answer 6

Anti-inflammatory
Analgesic
Anti-pyretic
Anti-platelet

Question 7

What are the adverse effects of typical NSAIDs?

Answer 7

GI: Ulcer formation, dyspepsia, nausea & vomiting
Renal: Na & H20 retention, peripheral edema, hypertension, vasoconstrict renal afferent arteriole
Asthma: Trigger bronchospasm
Skin rashes, swelling, nasal congestion, itching, anaphylactic shock
Easy bruising, bleeding

Question 8

What is the difference between COX 1 and COX 2?

Answer 8

COX 1 is in charge of housekeeping matters
COX 2 is in charge of inflammation