NSAIDs 2 Flashcards Preview

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Flashcards in NSAIDs 2 Deck (18)
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1

Which NSAID can be used for patent ductus arteriosus?

Indomethacin

2

Indomethacin - adverse effects

GI and CNS effects (highest incidence of the NSAIDS)

3

Indomethacin - interactions

Triamterene: nephrotoxicity

4

NSAID with highest incidence of GI and CNS side effects

Indomethacin

5

Which NSAID has renal-sparing effect?

Sulindac

6

Sulindac - indications

Rheumatoid arthritis
Adenomas in polyp disease

7

NSAID with analgesic effect comparable with morphine

Ketorlac

8

Ketorlac - indications

Post-op in dentistry and ophthalmology

9

NSAID not used long term

Ketorlac - limited to 5 days treatment

10

Piroxicam - indications

Chronic rheumatoid arthritis

11

The only non-acid NSAID

Nabumetone

12

Diclofenac - indications

Osteoarthrits

13

COX2 inhibitors (1 drug)

Celecoxib

14

How does celecoxib differ from other NSAIDs?

No platelet aggregation inhibition
No GI toxicity

15

Which NSAID is associated with decreased risk for which cancer?

Celecoxib - colon cancer

16

Celecoxib - indications

Rheumatoid arthritis
Osteoarthritis

17

Celecoxib - adverse effects

Cardiovascular events

18

Celecoxib - interactions

Fluconazole, fluvastatin and zafirlukast inhibits metabolism