NSAIDs 2

Question 1

NSAID medications

Answer 1

Ibuprofen Naproxen Indomethacin Aspirin Celecoxib Meloxicam Diclofenac Trolamine salicylate

Question 2

NSAID indications

Answer 2

analgesia antipyretic anti-inflammatory

Question 3

Aspirin indications

Answer 3

analgesia antipyretic anti-inflammatory antithrombotic

Question 4

NSAID MOA

Answer 4

reversibly inhibits COX-1 and COX-2 enzymes to decrease prostaglandin formation

Question 5

how is Aspirin’s MOA different from other NSAIDS?

Answer 5

it irreversibly binds to COX enzymes, other NSAIDs reversibly bind

Question 6

general NSAID’s AE

Answer 6

N/V, dyspepsia, ulcers, GI bleeding, increased BP, nephrotoxicity, CV risk

Question 7

Rare Aspirin AE

Answer 7

skin rash, bleed and bruising,

photosensitivity,

bronchospams,

Raye Syndrome in Children

Question 8

NSAIDs common routes

Answer 8

PO

topical

IM

IV

Question 9

Aspirin common routes

Answer 9

PO rectal

Question 10

what NSAIDs are antithrombotic?

Answer 10

Aspirin

Celecoxib

Diclofenac

Trolamine Salicylate

Meloxicam

Question 11

If you have GI risk which NSAID is the safest to take?

Answer 11

Ibuprofen (motrin, Advil)

Question 12

If you are at CV risk what is the safest NSAID to take?

Answer 12

Naproxen

Question 13

When should you avoid taking Celecoxib?

Answer 13

If you are at CV risk

Question 14

If you hae CV risk what NSAID should you avoid?

Answer 14

Celexocib

Question 15

If you have CV risk which NSAID is safest to take?

Answer 15

Naproxen

Question 16

If you have GI risk which NSAIDs are safe for you to take?

Answer 16

Celecoxib, Ibuprofen

Question 17

NSAIDs administered by what route give the lowest dose and for the shortest duration?

Answer 17

Topical

Question 18

T/F: someone with CHF shouldn’t take NSAIDs because it will increase their fluid retention

Answer 18

TRUE

Question 19

T/F: NSAIDs blunt the action of cardiovascular drugs?

Answer 19

TRUE

Question 20

If a patient is taking Ibuprofen, what should you watch out for?

Answer 20

Elderly, poor kidney function, history of GI bleed, any CV issues