OB-Gyn Flashcards

1
Q

a 66-year-old female with mass she felt in her left breast on recent breast self-examination.

No nipple discharge, hx of breast or other cancers.

Physical examination confirms painless, firm, irregular and immobile lump in the superolateral quadrant of the left breast

there are no evident overlying skin changes and there is no notable axillary lymphadenopathy on palpation.

This presentation is concerning for…

A

breast CA

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2
Q

Patient p/w:

  • unilateral localized breast pain w/ associated tenderness, erythema, warmth
  • Cracked nipples/fissure +/- purulent d/c
  • systemic sxs
A

Acute mastitis

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3
Q

Acute mastitis is most common in what population?

A

lactating women

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4
Q

MC pathogen responsible for acute mastitis and breast abscess?

A

staph aureus

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5
Q

1st line tx for acute mastitis…

A

supportive care/NSAIDs, breast pump

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6
Q

Anti-staph abx available for acute mastitis

A

dicloxacillin, nafcillin, cefazolin

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7
Q

Tx for breast abscess…

A

I & D or needle aspiration

+

nafcillin/dicloxacillin/cefazonlin + metronidazole

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8
Q

MC breast d/o in women 30-50 yo (reproductive age)?

A

fibrocystic breast

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9
Q

30-50 yo patient presents with breast mass on both breasts that changes in size with menstruation.

Reports worsening just before period begins.

initial DDx?

A

fibrocystic breast

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10
Q

On physical examination of a reproductive aged female, you notice multiple nodular, mobile, smooth round lumps bilaterally

Found in upper-outer /tail of spense

A

fibrocystic breast

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11
Q

Patient complains of a firm, nontender, solitary well circumscribed lump in the breast

it is freely mobile and feels rubbery to the touch.

doesn’t change with menstrual cycle

A

Fibroadenoma

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12
Q

First diagnostic test performed for breast mass that has suspicious features?

A

mammogram

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13
Q

Imaging of choice for fibrocystic/fibroadenoma?

A

ultrasound

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14
Q

what offers definitive dx of fibroadenoma?

A

FNA/Bx showing “swirl” collagen

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15
Q

Patient presents with:

mass felt in left breast

immobile, painless, firm, irregular lump

+/- bloody nipple d/c

A

breast CA

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16
Q

4 risk factors for breast cancer?

A
  1. BRCA1 and 2
  2. increasing age (> 60 yo)
  3. Increased number of menstrual cycles (early menarche, late menopause, late pregnancy)
  4. increased estrogen exposure
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17
Q

MC type of breast CA?

A

infiltrating intraductal carcinoma

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18
Q

60 yo women presents with chronic eczematous itchy, scaly rash on nipples and areola with a breast lump at the tail of spence…

A

paget disease

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19
Q

60 yo women presents with red, swollen, warm and itchy breast

nipple retraction and peau d’orange.

What is suspected and what is the prognosis?

A

inflammatory breast CA

Poor prognosis

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20
Q

What is a sign of locally advanced breast CA?

A

axillary LAD

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21
Q

Which type of breast CA is responsible for 10% of cases and is often bilateral?

A

infiltrating lobular carcinoma

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22
Q

Red flags for malignancy on mammogram… (2)

A

spiculated, microcalcification

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23
Q

Which imaging modality should be used as first line image for women < 40 yo with breast mass?

A

ultrasound

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24
Q

What is a disadvantage of FNA for breast CA testing?

A

doesn’t allow receptor testing

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25
What type of Bx is the most accurate diagnostic test for breast CA?
open Bx
26
Tx of choice for early stage breast CA?
lumpectomy with sentinal node biopsy + radiation
27
What Tx can be used in PRE-menopausal women with estrogen receptor positive tumors?
tamoxifen
28
What tx is useful for POST-menopausal estrogen receptor positive tumors?
aromatase inhibitors (letrozole, anastrozole, exemestane)
29
What tx is useful for anti-HER2 breast CA?
trastuzumab.
30
USPSTF guidelines for breast CA screening?
mammo q 2 years from 50-74 start at 40 yo if increased risk factors
31
45 yo female presents with: post coital bleeding friable, bleeding cervical lesion on physical exam
cervical CA
32
MC type of cervical CA...
squamous cell carcinoma
33
MC area of spreading for cervical CA?
paracervical lymph nodes
34
Dx of cervical CA?
colposcopy + Bx
35
45 yo female presents with: - pressure in pelvis when straining - incomplete bladder emptying after urination - urinary incontinence
cystocele
36
4 diagnostics for cystocele...
1. POP-Q 2. US 3. MRI 4. VCUG
37
Tx of cystocele
flexible ring/pessary bladder mesh surgery
38
What is the primary cause of an AUB in a woman without identifiable anatomic lesion?
endocrine/hypothalamic-pituitary-ovarian axis problems
39
Pelvic exam for a true AUB will be...
normal
40
Gold standard Dx for AUB...
uterine dilation and curettage
41
Workup for AUB...
Labs + imaging urine preg CBC, iron studies, coags, progesterone, prolactin, FSH, LFTs US
42
Tx for AUB...
OCPs and NSAIDs
43
Dx of dysmenorrhea
urine preg + pelvic US
44
Primary dysmenorrhea has does or doesn't have an organic cause?
doesn't
45
Primary dysmenorrhea is often found in what age group?
teens-early 20s
46
Primary or secondary dysmenorrhea? increases in severity until end common in women aged 20-40
secondary dysmenorrhea
47
Menopause occurs with ____ months of amenorrhea at an average age of ____
12 months 51 yo
48
FSH level in menopause...
FSH > 30
49
6 contraindications for HRT for menopause
increased triglycerides endometrial CA Hx of breast CA Heart disease, Stroke, DVT, PE Hx
50
what population should not use estrogen solo therapy to treat menopause sxs?
intact uterus
51
Full term infant...
37-42 weeks gestation
52
TPAL =
T = full term P = preterm A= abortions before 20 wks L = living children
53
Chadwick's sign...
bluish discoloration of vagina/cervix in pregnancy
54
2 skin changes in pregnant women...
melasma/chloasma linea nigra
55
hegar's sign...
softening between uterine fundus and cervix
56
at 12 weeks the uterus is at ______ at 20 weeks the uterus is at ____
12 weeks = symphysis pubis 20 weeks = umbilicus
57
HR of fetus...
120-160
58
Which labs will increase and decrease in pregnancy?
cholesterol increase BUN/Cr decrease
59
9 labs to be completed at first prenatal visit...
CBC blood type, RH factor, antibodies to blood group antigens Random glucose VDRL (RPR) Hepatitis B Rubella Urine Pap smear (if less than 1 year since last) Group B streptococcus
60
5 components present at every prenatal visit
Maternal weight Blood pressure fundal height fetal size and presenting part urine dipstick for protein, glucose, ketones
61
Screening at 10-13 weeks...
PAPP-A, nuchal translucency (downs, turners, trisomy 13, 18)
62
Screening at 15-18 weeks?
AFP/quadruple screen
63
Screening at 18-22 weeks...
official anatomical sonogram
64
Screening at 24-28 weeks...
Glucose Challenge Test
65
Screening at 28 weeks...
Rhogam if woman is RH negative
66
Screening at 32 weeks... (4)
CBC, VDRL, G/C, GBS
67
Recommended weight gain for an average weight woman during pregnancy...
20-35 lbs
68
A positive nonstress test during labor is...
2 accelerations in 20 minutes up 15 beats for 15 seconds
69
is a positive NST good or bad during labor?
good
70
Oxytocin challenge test (or Contraction Stress Test) is positive if...
late decelerations with each contraction
71
Is a positive oxytocin challenge test good or bad?
bad
72
What FHR change? rapid FHR drop with return to baseline
variable deceleration (benign to severe, indicates cord compression)
73
What FHR change? FHR drop at the end of contraction
Late deceleration | always worrisome, indicates uteroplacental insufficiency
74
Consistent _____ after a contraction can indicate fetal distress
decelerations
75
Outpatient Tx of PID...
250 mg ceftriaxone IM x 1 dose + Doxy 100mg BID x 14 days +/- Metronidazole 500 mg BID x 14 days
76
50-year-old female with pelvic pressure reports and a sensation of a mass present in the vagina. She reports chronic constipation and a sensation that the rectum is not completely emptied following a bowel movement. Occasionally, she experiences episodes of fecal incontinence.
Rectocele
77
What type of abortion? bloody vaginal discharge before 20 weeks of gestation with or without uterine contractions closed cervix
threatened abortion
78
What type of abortion? dilated cervical os with the passage of some but not all products of conception before 20 weeks of gestation
incomplete abortion
79
What type of abortion? dilated cervical os without passage of tissue before 20 weeks of gestation
Inevitable abortion
80
What type of abortion? death of the fetus before 20 weeks of gestation, with products of conception remaining intrauterine
Missed abortion
81
What type of abortion? expulsion of all or part of the products of conception before 20 weeks of gestation
Spontaneous abortion
82
Tx of candidal vaginitis?
fluconazole 150mg PO x 1, repeat in 7 days
83
Tx of BV (3)
metronidazole 500 mg PO BID x 7 days or metronidazole 750 mg QD x 7 or clindamycin intravaginal gel x 7 days
84
3 diagnostics of bacterial vaginosis...
pH > 4.5 (bacterial = basic) (+) whiff test Clue cells
85
Patient presents with: malodorous green/yellow frothy vaginal d/c strawberry cervix
Trichomoniasis
86
Tx for trichomoniasis...
metronidazole 2g PO x 1
87
Pt. p/w painful intercourse recurrent UTIs despite treatment thin appearing vaginal mucosa
atrophic vaginitis
88
Tx for atrophic vaginitis
conjugated estrogen cream
89
trichomoniasis vaginal pH...
5-6
90
vulvovaginal candidiasis vaginal pH
4-4.5 (normal)
91
bacterial vaginosis vaginal pH...
> 4.5