Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

BioChem > Obesity 1-2 > Flashcards

Obesity 1-2 Flashcards

(55 cards)

Start Studying
1
Q

Obesity is diagnosed by what

A

BMI and waist circumference
WC>40 in men
WC>35 in women
-best if used together

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Gold standard to diagnose obesity

A

Dual energy Xray absorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What percentage of american adults are overweight or obese

A

2/3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Complications with obesity

A

T2 diabetes
Cardiovascular problems

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Metabolic syndrome precedes what

A

diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Metabolic syndrome predisposes people to what conditions

A

CVD & diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Met syndrome diagnosis

A

3 of 5
Waist circumference
Hyperglycemia (>100 FBG)
Dyslipidemia
Hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cause of Met syndrome

A

Obesity and sedentary lifestyle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Met syndrome is associated with

A

Obesity that predisposes people to CVD and diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Diabetes can cause

A

Neuropathy, retinopathy (blindness), circulation problems, nephropathy, CVD!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Diabetes is characterized by what

A

HYPERGLYCEMIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Diabetic FBG/ RBG

A

Normal 80-100
Prediabetic 100-125
Diabetic >125
RBG>200 random blood glucose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Type 2 diabetes

A

Insufficient insulin production or insulin resistance causes hyperglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Type 2 diabetes- obese?

A

Pts are often obese and sedentary (not all though)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What diagnosis comes before Type 2 diabetes

A

Metabolic syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Insulin is what kind of hormone/ secreted from where

A

Anabolic hormone that signals fed state
Secreted by beta cells of pancreas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Insulin inhibits what

A

Glucagon, gluconeogenesis/ ketogenesis, lipolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Glucagon is what kind of hormone/ secreted from where

A

Catabolic hormone
secreted from Alpha cells of pancreas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Glucagon stimulates what

A

glycogenolysis, gluconeogenesis, ketogenesis, lipolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Obese people and insulin secretion

A

Obese people secrete more insulin to have same effect on blood levels than normal people

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Hemoglobin A1C

A

Diagnostic of DM when over 6.5%
Provides estimate of glucose levels from last 3 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Metformin

A

Inhibits gluconeogenesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

If metformin isnt working what comes next

Study These Flashcards
A

Injections of insulin

24
Q

Obesity can have what effect on liver

Study These Flashcards
A

Nonalcoholic liver disease- accumulation of TAG in liver, higher risk for liver cancer/ cirrhosis

25
Most widely prescribed medication?
Metformin
26
Genetic factors of obesity
Adopted children resemble biological parents
27
SNP's can cause
Obesity
28
Leptin is made from where
Adipose tissue
29
Do obese people have leptin
they have more leptin, but have developed leptin resistance (like insulin)
30
Leptin signals what
Satiety
31
What is the cause of obesity
Not a single cause due to genetic / behavioral/ environmental
32
Genetics can play what role in obesity
Can predispose someone to obesity
33
Android (apple)
Higher risk of developing chronic conditions WHR>.8 women WHR>1.0 men
34
Android tissue
High rates of lipolysis, promotes release of FFA, promotes release of Leptin
35
Gynoid (pear shaped)
Decreased risk for chronic conditions Lower body obesity
36
Gynoid tissue
Larger adipocytes Lower rates of lipolysis FFA released into blood and used for energy by muscle but NOT LIVER
37
Increasing size of adipocytes
Hypertrophy
38
Increasing number of adipocytes
hyperplasia
39
Adipose tissue behaves like
An organ
40
Adipose tissue releases
ADIPOKINES
41
Adipokines effect what
appetite, satiety, inflammation
42
Leptin
Suppresses appetite
43
Insulin
Suppresses appetite
44
Ghrelin- where does it come from
Increases appetite Stomach
45
Adiponectin comes from where
Adipocytes
46
Obese people have what levels of these hormones
Increased leptin (but less response) Increased insulin (less response) Decreased ghrelin Decreased adiponectin
47
Leptin comes from where
Adipocytes signals satiety
48
Adiponectin signals satiety by inhibiting
Orexigenic signalling
49
Orexigenic
stimulates hunger
50
Anorexigenic
Stimulates satiety
51
Leptin is assoc with what
Fat mass, higher in obese people ( but they have leptin resistance)
52
Hunger hormone
Ghrelin
53
Obese people have what levels of ghrelin
Reduced levels
54
Ghrelin is what kind of hormone
Orexigenic
55
Obese people have what levels of adiponectin
LOWER- but made in adipocytes

BioChem (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions