Oesophageal pathology Flashcards Preview

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Flashcards in Oesophageal pathology Deck (16):
1

Most common oesophageal cancer=
caused by ___

adenocarcinoma
reflux->Barrett's

2

Types of malignant oesophageal cancers (2)

adenocarcinoma
squamous cell carcinoma

3

red flags for oesophageal cancer

dysphagia (bolus sensation)
odynophagia
upper GI bleed
anaemia
wt. loss

4

Palliative options for oeso ca

chemo, radio (preserves swallow) stent

5

Potentially curative options for oeso ca

surgery (better cure rates)
chemoradiotherapy (less complications)

6

Stage oeso ca by

CT PET, EUS and laparoscopy
(CT doesnt show if has spread to peritoneum)

7

Acute oesophagitis is rare/common
caused by

rare
chemical ingestion
immunocompromised infection eg. CMV, herpes, candida

8

Chronic oesophagitis is caused by _+_

Reflux (common)
Crohn's (rare)

9

Barrett's is either due to ___ of gastric glandular epithelium or ___ of oesophageal stem cells

expansion
differentiation

10

In reflux as a cause of chronic oesophagitis=
basal cell endothelial ___ w intraepithelial _+_+_ and elongation of ____

expansion
neutro, lymphocytes ad eosino
connective tissue papillae

11

Allergic oesophagitis is ___ inflammation in ___ individuals who are young/old

eosinophilic, in atopics, young

12

Diagnosis of allergic oesophagitis is by :

pH probe -ve for reflux
eosinophilia in blood
corrugated horizontal oesophagus on endoscopy

13

treatment for allergic oesophagitis

steroids, cromoglicate, montelukast

14

Benign oesophageal tumours =

squamous papilloma - HPV related and asymptomatic

15

Oeso squamous ca is linked to

Vit A/zinc deficiency, strong tea, alcohol, smoking, HPV, oesophagitis

16

Oeso squamous cell ca produces

keratin perals