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Flashcards in OKAPS Flashcards- Cornea Deck (83):
1

What disease is associated with Cogan's syndrome

PAN

2

IK and deafness

syphillis

3

Where are accessory lacrimal glands

Wolfring- tarsus, Krause- conjunctival fornices

4

Enlarged corneal nerves

KCN, refsums's NF, PPMD, Fuch's Reiss Bucklers

5

Findings in Terrien's marginal degeneration

high ATR astigmatism in opposite angle of thinning

6

Findings of Ehlers Danose

KCN, blue sclera, high myopia

7

Which mucopolysaccharidoses are assocaitd with corneal clouding?

All but hunter's and sanfilipinos

8

Causes of corneal verticillatea

amiodarone, antimalariesals, tamoxifen, fabry's disease

9

cause of Fabry's disease

deficiency of alpha galactosidase

10

Histopathology of Salzman's

replacement of bowman's with hyaline

11

PUK+positive HbsAg

PAN

12

Ocular features of PAN

PUK, necrotizing scleritis, secondary Sjorgen's

13

Noninflammatory slowly progressive thinning of peripheral cornea begins superiorly has associated vascular pannus

Terrien's

14

Systemic features of keratconus

Down's, atopy, marfan's ehlers danose, MVP

15

Which anti-Epstein Barr virus antibody does not peak during first 6-8 weeks?

EBNA

16

Corneal clouding in infants

S infectious Trauma - Ulcer-Metabolic Peter's Dystrophy

17

HLA-DR3, tearing, small corneal epithelial lesions

Thygeson's

18

Causes of IK

syphillis, herpes, TB, leprosy, rubeola, EBC, chlamaydia, onchocerca

19

systemic association with SLK

Thyroid

20

shiledl shaped anterior subcaspular or PSC opacaities

atopic

21

staining pattern of RGP lens overwear

3 and 9 o'clock

22

where does glucose for corneal epithelium come from

aqueous humor

23

which antiviral produces preauricular lymphadenopathy

idoxurine

24

hyperkeratotic lesions of palms, elbows,

tyrosinemia type II

25

very short person photophobic with polychromatic conjunctival and corneal crystrals

cystinosis

26

rx for cystinosis

cysteamine

27

difference between neonatal and adult inclusion conjuncitivitis

follicular response rare in kids

28

difference in papillae between atopic, vernal and GPC

atopic- papillae in inferior palpebral, VC, GPC in superior tarsus.

29

avg corneal diameter adult

12.5x11.5, vert by horizontal

30

acg corneal diameter kid

9.5x10.5

31

power of cornea

49 front, -6 back

32

Descemet's membrane

fetal banded anterior, adult nonbanded, thickens with age

33

assocations with atopic conjunctivitis

KCN, PSC (Maltese cross), HSV keratitis

34

ddx chronic follicular conjuncitivitis

chlymadia, mediacmentosa, HSV, Lyme, parinaud's, atopic

35

Adenovirus with pharynconjunctival fever

3,4,5,7. 8,19,37 with epidemic

36

unilateral follicular conjuncitivitis, penumonitis

Newcastle's occurs in pouletry handlers

37

HPV viruses associated with CIN

16, 18, actinic exposure

38

rare variant of squamous cell with malignant goblet cells

Mucoepidermoid, stains with mucicarmine, alcian blue

39

Seen in halifax, North carolina, bilateral dyskeratotic lesions

benign heriditary intraepithelial dyskeratotis AD

40

lacrimal and parotid gland swelling and KCS due to sacroid, TB, lymphoma, leukemia

Mikulicz's syndrome

41

Cogan's syndrome

IK with Menier's like vestibular dysfunciton, 80% progress to deafness without steroids

42

ddx of keratitis with vestibuloauditory symptoms

syphilis, PAN, Wegner's sarcoid, SO, VKH, cerebellpontine angle tumor.

43

bilateral, goldben brown deposits

spheroidgal degeneration

44

corneal mucopolysaccharidoses with retinopathy only

Hunter's, sanfilipo's

45

Mucopolysaccardigoses with no corneal clouding or retinopathy

Sly's

46

Mucopolysaccharidoses inheritance

AR except Hunter's, most have corneal clouding, retinopathy, and optic atrophy

47

Sphingolipidoses inheritance

AR except Fabry's X linked, most affect retina except fabry's

48

alpha galactosidae deficiency

Fabry's disease

49

Findings of fabry's disease

corneal verticillata, cataracts, vascular anomalities of heart kidney, brain

50

ddx of corneal verticillata

amiodarone, chlooroquine, indomethjacin, pheothiazine

51

HDL deficinecy, relapsing polyneuropathy, deep stromal opacities

Tangier's disease (AR)

52

diffuse clouding, denser in periphery

fish eye disease

53

arcus

Hyperlipoporteinemia types 2,3,4

54

findings of cystinosis

sal and pepper fundus, no visual symptoms, polyuria, retardation, cystine crystals in conj, cornea, iris, lens retina

55

rx of cystinosis

cysteamine

56

refractile branching linear opacities, triad of painfu hyperkertotic skin lesions, keratitis, and mental retaration

Tyrosinemia type II ®

57

young kid with reccurrent HSV keratitis

tyrosinemia type II

58

corneal melt only in cornea, spreads circumferentially

Mooren's ulcer

59

what hypersensitivity, and what associations with Mooren's

type II, with hep C, crohn's

60

painless progressive bilateral stromal thinning starts superiorly

Terrien's

61

causes of PUK

RA, Wegner's relapsing polychondrisis, PAN, SLE, slceralderma behcet's

62

organisms which can penetrate cornea

gonorrhea, cornebacterium, shigella, H aegyptis listeria

63

HSV resides in what ganglion

Gasseiran

64

immune ring in cornea

type III hypersensitivity

65

differences between HSV AND HZV dendritie

HZV- no terminal bulbs

66

fungi

septate- fusarium aspergillus, cuvulaea, nonseptate- mucor

67

dimorphic fungi

histo, blasto, cocci

68

book answer for rx for aspergiillus

clotrimazole

69

recurrence of acanthomeba after PK

30%

70

rx for microsporida keratitis

fumagillin

71

antigens for eBV

EBNA, VCA-IgM last for life. Others peak at 6-12 weeks.

72

KCN histology

breaks in bowman's

73

associations of eratoglobus

connective tissue disorderes, LCA,

74

pathology of Map, dot fingerprint

epithelial redublication

75

Anterior corneal dystrophies

map,dot, fingerprint, messman's, gelatinous, resibuckler's thiel behke

76

AR corneal dystrophies

macular, gelatinous

77

difference between reiss buckler's thiel benhke

reiss- curly filaments on EM, thiel- saw toothed epithelium

78

yellow crystals below bowman's hyperolipidemia

central crystaline schnder's

79

dystrophy where vision not affected

fleck, tiny wreath like opacitiy

80

nonprogresive, vision not affected, tiles in the floor

central cloudy of francois, similar to crocodile shagreen

81

brown mclean syndrome

peripheral corneal decompensation in aphakicpatients central cornea clear

82

MEN 1

pituitary, parathyroid and pancreas

83

MEN 2

mdullary thrydoid, peho, parathyroid, can get GI neuromas