Oncology Flashcards Preview

ACNP REVIEW > Oncology > Flashcards

Flashcards in Oncology Deck (15)
1

Horner's Syndrome

nerve pathway disruption causing decreased pupil size, drooping eyelid, and decreased sweating on affected side of face

D/T stroke

2

Diagnostic criteria for multiple myeloma

Bone Marrow plasma cell > 10%
Biopsy proven plasmacytoma
Presence of serum/urine M-protein
And CRAB
Calcium > 11.5
Renal impairment creat > 2
Anemia Hgb <10 or 2 g/dL below normal
Bone lesions

3

Monoclonal Gammopathy of undetermined significance (MGUS) definition and management

< 3 g M spike
< 10% bone marrow plasma cells and
No anemia, bone lesions, hypercalcemia or renal failure

Management: observation

4

Smoldering myeloma diagnostics and management

M spike > 3 g/dL
BM plasma cell >10%
No CRAB

5

Common CNS complication of cancer

Cauda equina syndrome

6

Cauda equina syndrome definition and management

Med/Surg emergency
Affects nerves L1-5 and S1-5
Saddle anesthesia
Disruption of bowel and bladder function

Management: surgery, steroids, radiation

7

SVC syndrome

Tumor presses on superior vena cava causing swelling of face, neck, and/or arms. venous distention of axillary, subclavian and jugular veins. Persistent cough, SOB, hoarseness, swelling around the eyes,

Trx: relieve obstruction, radiation, supportive measures, O2, steroids

8

IVC syndrome

Vascular complication d/t to cancer causing clot in IVC showing tachycardia and lower extremity edema

9

Most common malignancy for female's surviving Hodgkin's lymphoma

breast cancer

10

Differential diagnoses for lymphadenopathy

CHICAGO
Cancers
Hypersensitivity syndromes
Infections
Connective tissue disorders
Atypical lymphoproliferative disorders
Granulomatous lesions
Other

11

Hodgkin's lymphoma risk increases 3 fold due to this exposure

Ebstein Barr Virus

12

FISH

Fluorescence in Situ Hybridization
Can diagnose CML, ALL, and Down's
Used to diagnose, evaluate progress and remission

13

Doxorubicin (Cyclophasphamide in R-CHOP) side effect and treatment of side effect

Irritation to the lining of bladder causing Hemorrhagic cystitis (hematuria)
Treatment: stop medication, continuous bladder irrigation, pain meds, blood transfusions

14

Risk for anti-angiogenesis agents (Bevacizumab)

prevents cancer from accessing new vasculature
Side effect: perforation, ileus, bleeding

15

Musculoskeletal complication of cancer and treatment

Bone metastasis and hypercalcemia
Trx: biphosphonates (Alendronic or Zoledronic acid) and treatment of hypercalcemia
(IV fluids, calcitonin)