Oncology and Palliative

Question 1

Which cancer is specific for Cannon-ball mets in lung

Answer 1

Renal Cell Carcinoma

Question 2

Pre-terminal state patient in Seizure management

Answer 2

S/C Midazolam

Question 3

X ray finding in Hypertrophic pulmonary osteoarthropathy

Answer 3

Periostitis of Radius and Ulna

Question 4

Leukoerythroblastic Blood Picture

Answer 4

presence of immature red blood cells and immature white blood cells

Question 5

Family History of Colon Cancer + Intermittent Heavy Vaginal Bleeding in Post menopausal women

Answer 5

Hereditary Non-polyposis colorectal cancer

Question 6

Serine/threonine kinase 11 (STK11) gene associated cancer

Answer 6

Peutz–Jeghers syndrome

Question 7

Management of Refractory haematuria secondary to bladder carcinoma

Answer 7

Selective iliac artery embolisation

Question 8

Management of radiation-induced haematuria

Answer 8

Hyperbaric Oxygen Therapy

Question 9

Gold standard for diagnosing endometrial cancer.

Answer 9

Hysteroscopy with endometrial biopsy

Question 10

Ca Cervix Management

Answer 10

Stage 1 - Conservative Management
Stage 2a - Radicle Surgery (<4 cm)
Stage 2b - Chemotherapy (>4 cm)
Stage 3 - Chemotherapy

Question 11

Management of Small Cell Lung Cancer with Spread to Hilar Nodes

Answer 11

Combination Chemo and Radio

Question 12

Common Chemo Regimen for Squamous Cell Lung Cancer

Answer 12

Cisplatin + Etoposide

Question 13

Cancer patient with nausea + vomiting + anxiety

Answer 13

Add Lorazepam to already antiemetics

Question 14

Management of Capsular Pain due to liver mets

Answer 14

Dexamathasone

Question 15

Ovarian Cancer Common Chemo Regimen

Answer 15

Carboplatin + Paclitaxel

Question 16

Most commonly associated cancer with Parkinsons Disease

Answer 16

Malignant Melanoma

Question 17

Antiamphiphysin antibodies are seen in

Answer 17

stiff-person syndrome seen in breast or lung cancer

Question 18

Anti-Yo antibodies seen in

Answer 18

Ovary and Uterine Cancers - Causes Ataxia

Question 19

Burkitt’s lymphoma C/F

Answer 19

rapidly growing tumour with spontaneous tumor lysis = very high lactate and uric acid levels

Question 20

Common Chemotherapy agent causing peripheral neuropathy

Answer 20

Oxaliplatin

Question 21

Most effective treatment for SVC obstruction caused by lung cancer

Answer 21

SVC Stenting

Question 22

Risk factors for Ovarian Cancer

Answer 22

• Early Menarche
• Late Menopause
• Nulliparity

Question 23

Mantle radiotherapy complications

Answer 23

• Thyroid Disorders
• Breast Cancer

Question 24

Turmor Lysis Syndrome Lab Findings

Answer 24

• Hyperuricemia
• Hyperphosphatemia
• Hyperkalemia
• Hypo*calcemia

Question 25

SMART (Stroke-like Migraine Attacks after Radiation Therapy) syndrome C/F

Answer 25

Brain tumor surgery and radiotherapy done years ago now presented with stroke like features and headache

Question 26

First Line Agent for Neuropathic Pain

Answer 26

Pregabalin

Question 27

DOC for Palliative Care patient with Seizures

Answer 27

Levitiracetam

Question 28

Tamoxifen Side Effect

Answer 28

Increased risk of Blood Clots

Question 29

Ewings Sarcoma Poor Prognosis Factor

Answer 29

Anemia

Question 30

Glioblastoma Multiforme Inital Management

Answer 30

Gross Total Resection

Question 31

Glioblastoma Post-Operative Chemotherapy

Answer 31

Radiotherapy 60 Gy in 30 fractions with concomitant temozolamide followed by upto 6 cycles of adjuvant temozolamide

Question 32

To prevent Tumor Lysis Syndrome - Commonly used marker before Chemotherapy

Answer 32

LDH

Question 33

Cancer patient with new onset back pain and difficulty walking inital management

Answer 33

IV Dexamethasone

Question 34

Olaparib Mechanism of Action

Answer 34

Inhibits PARP enzyme

Question 35

DOC for Non Functioning Adrenal Cortical Adenocarcinoma

Answer 35

Mitotane

Question 36

DOC for virilizing adrenal cancers

Answer 36

Aminoglutethimide

Question 37

What is Klatskin tumor and what is the management

Answer 37

Cholangiocarcinoma at the hepatic hilum (area where the right and left hepatic ducts join) Management - Inoperable so Chemo with cisplatin and gemcitabine

Question 38

European Family with multiple family history of Ca Breast Genetic Test

Answer 38

CDKN2A - cyclin-dependent kinase inhibitor 2A

Question 39

Multiple Myeloma tumor marker with worse prognosis

Answer 39

Beta 2 Microglobulin

Question 40

Benefit of Ca Breast breast patient to take Tamoxifen

Answer 40

To prevent contra-lateral Ca Breast

Question 41

First line Chemotherapy agent for CLL

Answer 41

Fludarabine

Question 42

Prophylactic medication for patient to be started on fludarabine

Answer 42

Co-Trimoxazole

Question 43

Corrected serum calcium Equation

Answer 43

measured calcium (mmol/l) + [40 – serum albumin (g/L)] × 0.027.

Question 44

Post Radiation to Head patient presents with lethargy, sleepiness

Answer 44

Post Cranial Irradiation Somnolence syndrome

Question 45

Inital Management of SVC Obstruction

Answer 45

Dexamethasone + LMWH

Question 46

Most common side effect of Rituximab

Answer 46

Fever and Chills

Question 47

Chemotherapy Induced Vomiting Inital Management

Answer 47

Domperidone + Dexamethasone

Question 48

Management of Extravasation of Doxorubicin or Danorubicin to skin

Answer 48

Plastic Surgery Consult - Due to increased risk of Ulceration

Question 49

Indications for Platelet transfusion

Answer 49

<10,000 - In otherwise well patients (ie no fever or bleeding) <20,000 - Patient has a fever/other signs of sepsis <50,000 - If the patient is actively bleeding