Ophthalmic Flashcards Preview

Pharm I Fall 2016 NUNM Jensen > Ophthalmic > Flashcards

Flashcards in Ophthalmic Deck (29)
Loading flashcards...
1

What are agents that dilate the pupil called?

Mydriatics

2

What are agents that cause paralysis of accommodation?

Cycloplegics

3

What is an agent that causes pupillary constriction?

Miotic

4

What is seen with fluorescein dye in herpes keratitis?

Dendritic figure

5

What are three pharm interventions for keratoconjunctivitis sicca?

Artificial tears
Topical cyclosporine
Oral omega-6 FA

6

What is the MOA for decongestants in regard to conjunctivitis?

Constrict dilated arterioles of conjunctiva

7

Mild tx for allergic conjunctivitis includes: cool compress, antihistimine/decongestant, and lubricant. What does moderate and severe tx add?

Mod.: mast cell stabilizer
Sev.: steroid, NSAID, mast cell stabilizer

8

What are three decongestants used to constrict dilated arterioles of the conjunctiva?

Tetrahydrozoline
Naphazoline
Phenylephrine

9

What are two decongestant/antihistamine combinations?

Antazoline/Naphazoline
Pheniramine/Naphazoline

10

What are three antihistamines used to block H1 receptor sites for conjunctivitis?

Azelastine hydrochloride
Emedastine
Olopatadine

11

What are three Mast Cell Stabilizers used in conjunctivitis?

Ketotifen
Cromolyn sodium
Nedocromil sodium

12

What NSAIDS are used for conjunctivitis?

Ketorolac
Diclofenac sodium
Flurbiprofen
Suprofen

13

What are the two drugs of choice for bacterial conjunctivitis?

0.3% Tobramycin
Polymyxin B/Trimethoprim

14

For more severe infections of bacterial conjunctivitis what are the drugs of choice?

0.3% Ofloxacin
0.3% Ciprofloxacin

15

What are three Aminoglycosides used topically to treat conjunctivitis?

Gentamicin
Neomycin
Tobramycin

16

What are four Fluoroquinolones (broad spectrum antibiotics) used topically to treat conjunctivitis?

Ciprofloxacin
Ofloxacin
Gatifloxacin
Moxifloxacin

17

What treatment is indicated for confirmed gonococcal or chlamydial disease in the eye?

IV antibiotics

18

What topical antibiotic treatment is primarily reserved for prophylaxis of neonatal gonococcal and chlamydial infection?

Erythromycin ointment

19

What is the drug of choice for the treatment of HSV keratitis?

Trifluridine topical solution

20

What are three options for treating Cytomegalovirus keratoconjunctivitis?

Ganciclovir
Cidofovir
Foscarnet

21

What is the first line of therapy (category) for primary open-angle glaucoma?

Beta blockers
Prostaglandin analogs

22

For the treatment of glaucoma what beta blockers are nonspecific? (3)

Timolol
Levobunolol
Metipranolol

23

For the treatment of glaucoma what beta blockers is relatively B-1 specific?

Betaxolol

24

What is the advantage of Timolol and levobunolol (nonspecifics) over Betaxolol (B-1)?

They are more effective at lowering IOP

25

What beta blocker used for glaucoma is nonspecific with partial beta agonist activity?

Carteolol

26

What is the #1 prescribed prostaglandin analog used for glaucoma?

Latanoprost

27

What is the primary alpha-2 adrenergic agonist used for glaucoma?

Brimonidine

28

What are three carbonic anhydrase inhibitors used for glaucoma?

Dorzolamide
Brinzolamide
Acetazolamide

29

What is the MOA for carbonic anhydrase inhibitors (CAIS)?

Reduce IOP by decreasing bicarbonate production (by inhibiting CA) resulting in 40-60% decrease in AH secretion