Osteoporosis Flashcards Preview

Endocrinology > Osteoporosis > Flashcards

Flashcards in Osteoporosis Deck (15):
1

What is the ratio of women to men?

5:1

2

What percentage of bone is trabecular?

20%

3

Which diabetes type increases risk?

type 1

4

What type of scans are used most widely to measure BMD?

DEXA scans

5

What is the difference between T score and Z score?

T score: young female adult population mean
Z score: age matched female population mean

6

Ostopenia definition in terms of SD from norm?

BMD >1 but <2.5

7

Osteoporosis definition in terms of SD from norm?

BMD >2.5

8

severe osteoporosis definition in terms of SD from norm??

BMD >2.5 WITH fragility fracture

9

What dose of vitamin D supplement should be give to female over 65?

10ug

10

What dose of vitamin D supplement should be give to female over 65, who is housebound and frail?

20ug

11

How is zeledronic acid administered?

once year IV infusion for 3 years

12

What is denosumab and what does it target?

Fully human monoclonal antibody that targets and binds with high affinity and specificity to RANKL (receptor activator of nuclear factor-kB ligand)

13

What line of agent is strontium ranelate?

3rd line

14

When is strontium ranelate contraindicated?

if history of Thromboembolic Disease, IHD, Peripheral Arterial Disease, Uncontrolled Hypertension

15

What is teriparatide?

recombinant parathyroid hormone, once daily injection