Osteoporosis Flashcards
(16 cards)
give some risk factors for osteoporosis
Steroid use Hyperthyroidism, hyperparathyroidism, hypercalciuria Alcohol/tobacco Thin Testosterone reduced Early menopause Renal/liver failure Erosive/inflammatory boene disease Dietary calcium decreased/malabsopriton/T1DM
what is the T-score
number of SD the BMD is that from that of a healthy 30yo of the same sex
what investigations should you do in suspected osteoporosis
Xray and DEXA
what T score corresponds with osteopenia
-1 to -2.5
what T score corresponds with osteoporosis
-2.5 or worse
what age would you not require a DEXA before initiating treatment following a low trauma fracture
women >75yrs
what are some side effects of bisphosphonates
photosensitivity
GI upset
oesophageal ulcers
what is the first line treatment for osteoporosis
bisphosphonates - alendronic acid
how do bisphosphonates work
slow down osteoclasts
how should you take bisphosphonates
standing upright with lots of water
wait 30mins before eating or other meds
what supplements may be useful in osteoporosis
calcium and vit D
when could you use strontium ranelate
if severe intolerance of other agents and NO cardiovascular disease
what can you give hypogonadal men
testosterone
what is the Z score
a comparison of a persons bone density with that of an average person of the SAME age and sex
if cortical bone is affected, what fractures are common
long bone
if trabecular bone is affected, what fractures are common
crush fractures of the vertebrae