Polymyalgia rheumatica Flashcards
(8 cards)
1
Q
give the clinical features of PMR
A
subacute onset (<2 weeks) of BILATERAL aching, tenderness and morning stiffness in the
- shoulders
- hips
- proximal limb muscles
fatigue
fever, weight loss, anorexia, depression
2
Q
what time of day are symtpoms worst
A
morning
3
Q
give some abnormalities seen on blood test
A
raised CRP
ESR >40
Alk Phos raised in 30%
decreased CD8+ T cells
4
Q
what would you see on histology
A
vasculitis with giant cells and characteristic skip lesions
5
Q
how do you manage PMR
A
prednisolone
6
Q
how quickly would you expect to see a response to steroids
A
1 week
7
Q
what might a specialist prescribe a patient with PMR
A
methotrexate
8
Q
what condition overlaps with PMR
A
temporal arteritis