Pagets disease Flashcards
(7 cards)
1
Q
what is pagets disease
A
increased bone turnover associated with increased numbers of osteoblasts and osteoclasts
there is resultant remodelling, bone enlargement, deformity, weakness
2
Q
what are the clinical features of pagets disease
A
asymptomatic in majority
deep boring pain and bony deformity/enlargement
3
Q
what are some complications of paget’s disease
A
pathological fractures OA raised calcium nerve compression osteosarcoma high output CCF
4
Q
what will you see on blood results in pagets disease
A
raised ALP
normal calcium and phosphate
5
Q
what would you see on Xray in pagets disease
A
localised bone enlargement
patchy cortical thickening w/ sclerosis, osteolysis and deformity
6
Q
define sclerosis
A
abnormal hardening of body tissue
7
Q
how do you manage paget’s disease
A
analgesia
alendronic acid
