Ovarian cancer Flashcards Preview

Year 2 OBGYN > Ovarian cancer > Flashcards

Flashcards in Ovarian cancer Deck (19):
1

what is the most important independent risk factor for ovarian cancer? what are other risk factors?

- age

- family history
- BRCA-1
- nulliparity, infertility, endometriosis

2

is CA-125 a good screening technique for ovarian cancer?

no

3

is an adnexal mass in young women often benign or malignant? what does it usually consist of?

- benign
- functional cyst

4

what is the workup for an adnexal mass? what needs to be considered?

- BHCG
- transvaginal US

consider timing in cycle

5

what should be excluded in the workup for an adnexal mass in a postmenopausal woman? what exams should you do?

- endometriosis
- cyst
- abscess

- breast exam
- DRE
- mammography

6

what is the positive predictive value of US for adnexal masses?

low

7

what is the epithelial tumor marker?

CA-125

8

what are the malignant germ cell tumor markers?

- BHCG
- LDH
- AFP

9

what are the embryonal tumor markers?

- AFP
- BHCG

10

what is the endodermal sinus tumor marker?

AFP

11

what is the granulosa cell tumor marker?

inhibin

12

what are the treatment options for epithelial ovarian cancer?

- cytoreductive surgery
- chemo

13

what is the most lethal gynecological malignancy?

ovarian cancer

14

what are the presenting symptoms of a molar pregnancy?

- first trimester bleeding with size > menstrual dates
- elevated BHCG
- toxemia prior to 24 weeks gestation
- hyperemesis

15

what is the imaging modality of choice for gestational trophoblastic disease?

US

16

what % of molar pregnancies are invasive?

5-10%

17

what is the workup for a complete molar pregnancy?

- CXR
- CBC, CMP, clotting studies

18

what are the treatment options for a molar pregnancy?

- evacuating the uterus
- monitoring BHCG levels
- chemo (sometimes)

19

what are the sites of metastasis if a trophoblastic neoplasia occurs?

- lung
- vagina
- liver
- brain