Ovine Pulmonary Adenocarcinoma

Question 1

Definition

Answer 1

Progressive fatal chronic contagious virus related pulmonary adenocarcinoma

Question 2

Etiology

Answer 2

Betaretrovirus

Question 3

Epidemiology

Answer 3

Adult sheep 2-4yo, rare goats and muflons
Virus: aerosol or direct contact with young animals with infective nasal secretion->tatget cells->typell pneumocytes and club cells
Long incubation period
Chronic resp disease, mucous nasal discharge
Mortality 1-5%

Question 4

Gross

Answer 4

Anteroventral areas
Solitary nodules
White-gray, to confluent masses, firm irregular large
Airways with viscus foamy fluid
Necrosis

Question 5

Micro

Answer 5

Well delimited
Uncapsulated, heterogeneous, densely cellular, neoplastic mass