Pain Correlates-Falkenberg TBL Flashcards Preview

Block 5 Week 2 Dani > Pain Correlates-Falkenberg TBL > Flashcards

Flashcards in Pain Correlates-Falkenberg TBL Deck (48)
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1

Where do we find nociceptors?

skin, muscle, joints and visceral tissues

2

How do you get neuropathic pain?

primary lesion or dysfunction in the nervous system,
i.e diabetic neuropathy

3

What is sympathetic pain or CRPS?

Pain signals from the sympathetic nervous system become constant and severe, even though there is no obvious cause of pain. The mechanism by which this happens is complex and not fully understood.

4

What kind of pain is this:
relating to or denoting any disease or condition that arises spontaneously or for which the cause is unknown.

idiopathic

5

What makes the nervous system plastic?

windup
change of neurotransmitter
change of phenotype
sprouting
glial cells
hyperesthesia
allodynia
hyperlgesia

6

What are first line analgesic drugs?

acetaminophen
aspiring/NSAIDs
adjuvants

7

What are 2nd line or drugs to use when pain is out of control drugs?

opoids (sustained release or immediate release)
NSAIDs
adjuvants

8

What drugs do use for refractory pain (pain that persists longer than usual and isnt responding to the usual meds)?

spinal/epidural opoids (clonidine, local anesthetic)
selective nerve blocks
neuroablative procedures
Ketamine
total sedation

9

What are the major classes of analgesics?

NSAID's
P-aminophenol
Opiates
Local anesthetics, lidocaine

10

What are examples of NSAIDS?

ibuprofen, naproxen, ketoprofen, COX-2 inhibitor

11

What is an example of an P-aminophenol?

tylenol

12

What are examples of opiates?

morphine, oxycodone, fentanyl

13

What is an excellent anesthetic?

lidocaine

14

What is a common calcium channel blocker?

ziconotide

15

what are these:
Calcium channel blockers- ziconotide
Anticonvulsants
Selective serotonin reuptake inhibitors
Alpha-agonists
Multi-receptor drugs- Tapentadol (NE)
TRPV-1- antagonists

analgesics

16

What drugs target the cortex for pain relief?

anxiolytics, hypnotics, opoids, psychostimulants, anticonvulsants

17

What drugs target the thalamus for pain relief?

SSRI's, anticonvulsants

18

What drugs target the spinal cord?

Opoids, adrenergicagonists, SSRIs.

19

Where do you put a neural blockade?

spinal cord baby!

20

What can illicit pain relief at the pain receptors?

NSAIDs
Local Anesthetics

21

What does P.O stand for?

oral

22

What does P.R stand for?

rectal

23

What does Sub. Q stand for?

subcutaneous

24

How do you give someone a transmucosal administration of a drug?

via a sublingual lollipop

25

Why should you treat pain?

pulmonary function, CV function, mobility

26

The majority of drugs are (blank) rather than local. Why are local drugs so nice?

systemic
Because they have less systemic effects so less side effects

27

What is fentanyl?

100 X more potent than morphine (used in chronic pain patients)

28

What is preemptive analgesia?

prevent firing of pain nerves prior to surgery to increase recovery time and decrease risk of chronic pain.
(hit them with that multimodality, and do it before, during and after to prevent wind up)

29

What is additive and synergistic analgesia?

treating multiple types of receptors (multimodality) will have an additive affect and result in better pain relief

30

What is on-demand analgesia?

when the patient asks for it and you give it to them