Pancreas Flashcards

(70 cards)

1
Q

what organ is small, elongated, and located in the abdomen

A

pancreas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what makes up exocrine units of the pancreas

A

tubuloacinar glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

how are tubulacinar glands organized

A

grape bunches

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is the name of the endocrine units of the pancreas

A

islets of Langerhans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

where are the exocrine units of the pancreas found

A

they surround the islets of langerhans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what do the pancreas cells have in the them

A

digestive enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is the main digestive enzymes found in pancreas cells (4)

A

trypsinogen, chymotrypsinogen, pancreatic lipase, and amylase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

in what region of the pancreas are the endocrine units mostly in

A

tail region

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what do the endocrine unit cells surround

A

pancreatic acini

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what 3 major types of cells do the islets contain

A

alpha, beta, and delta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what hormone do alpha cells produce

A

glucagon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what hormone do beta cells produce

A

insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what hormone do delta cells produce

A

somatostatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what leads to decreased glucagon and insulin levels

A

somatostatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what function of the pancreas produces enzymes that break down food

A

exocrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what function of the pancreas secretes hormones that affect carbohydrate metabolism

A

endocrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

T or F: exocrine tissue secretes pancreatic juice

A

T

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what are the major hormones involved in stimulated secretion?

A

secretin and CCK

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is the function of secretin

A

stimulates the secretion of the alkaline aqueous component

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what is the function of CCK

A

stimulates the secretion of the enzyme component

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

when is secretin released

A

in response to acid in the small intestine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

when is CCK released

A

in the presence of fats or aa in the dueodenum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what hormone is responsible for the release of enzymes

A

CCK

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what is the content of pancreatic juice?

A

mix of enzyme-rich secretion and an aqueous alkaline secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
what cells secrete enzymes
acinar cells
26
what cells secrete alkaline fluid
duct cells
27
what kind of juice do the cells of the upper ducts of the pancreas secrete
isotonic
28
what is the isotonic juice rich in
bicarbonate
29
what is the function of the alkaline pancreatic secretion
neutralize the acid arriving from the stomach
30
what kind of environment do pancreatic enzyme work in
neutral or slightly alkaline
31
what does the lumen of micelles absorb in neutral or slightly alkaline pH
fat
32
what protects the intestinal mucosa from excess acid
pancreatic alkaline secretion
33
what does excess acid in the duodenum lead to
ulcers
34
what kind of enzymes are proteins
proteolytic enzymes
35
what are these examples of: trypsin, chymotrypsin, elastase, collagenase, and peptidase
proteins
36
what kind of enzymes are lipids
digestive enzymes
37
what are the main digestive enzymes of the pancreas
lipase and lecithinase
38
what splits pancreatic amylase
Carbohydrates
39
what hormones do the endocrine cells of the pancreas secrete (3)
insulin, glucagon, and somatostatin
40
what cells produce glucagon and insulin
alpha and beta
41
are benign tumor life threatening
no
42
what kind of tumor do not invade surrounding tissues and do not metastasize to other parts of the body
benign
43
def? growth of a malignant tumour within the small pancreas organ.
pancreatic cancer
44
what is the most common cancer of the pancreas
adencarcinma of the pancreas
45
A less common, and typically far less aggressive form of pancreatic cancer, is
islet-cell tumor
46
what kind of disorder is cystic fibrosis
autosomal recessive disorder
47
def? characterized by dysfunction of mucous and exocrine glands throughout the body.
cystic fibrosis
48
what do the acini and ducts fill with cystic fibrosis
mucus
49
what is an effect of the small cysts filled with mucus in cystic fibrosis
prevention of pancreatic secretions
50
what parts of the body doe cystic fibrosis affect
lungs and digestive system
51
what disease does this child have? the child's body can't process or absorb nutrients properly, especially fats. The child has problems gaining weight, even with a normal diet and a good appetite.
CF
52
def? inflammation of the pancreas due to auto digestion of the pancreas
pancreatitis
53
what causes auto digestion of the pancreas
reflux of bile of duodenal contents into pancreatic duct
54
what kind of pancreatitis occur suddenly and last for a short period
acute
55
does acute pancreatitis resolve
yes
56
does chronic pancreatitis resolve itself
no
57
what kind of pancreatitis is slow destruction
chronic
58
what causes pancreatitis
gallstones or alcohol abuse
59
what disease? swollen and tender upper abdomen, nausea, vomiting, fever, rapid pulse
acute pancreatitis
60
T. or F: with chronic pancreatitis there can be no pain
T
61
if someone has fatty stools what disease do they probably. have
chronic pancreatitis
62
what do these test look for: Fecal Fat analysis Sweat analysis Secretin stimulation test Image Enzyme test
pancreatic function
63
what does a secretin stimulation test measure
the ability of the pancreas to respond to secretin
64
when secretin is release what does it tell the pancreas to do
secrete a fluid with a high conc of bicarbonate
65
what does the image test detect
obstructions or tumors
66
what is the most sensitive pancreatic test
secretin stimulation test
67
what is the most useful test for cystic fibrosis
sweat electrolyte
68
what enzyme will increase in the serum of a pt with acute pancreatitis
amylase
69
what is the most sensitive indicator of acute pancreatitis
urine amylase
70
does amylase or lipase last longer in the serum of a pt with acute pancreatitis
lipase