Parvoviridae

Question 1

T/F: Parvoviridae is very stable,, making disinfection of contaminated premises very difficult

Answer 1

True

Question 2

T/F: Infection of Parvoviridae leads to large intranuclear inclusion bodies

Answer 2

True

Question 3

T/F: human parvovirus B19 is the same found in dogs and can be transmitted to humans from dogs or cats

Answer 3

False, B19 is different from that seen in dogs and cats and there is no evidence of transmission

Question 4

What disease does feline parvovirus cause?

Answer 4

Feline panleukopenia (FPV)

Question 5

T/F: FPV is not highly contagious or fatal

Answer 5

False, it is highly contagious and often fatal in cats and sever in kittens

Question 6

How is FPV maintained in a population?

Answer 6

By environmental persistence

Question 7

What are 3 ways FPV can be transmitted?

Answer 7

1. Oro-nasally by infected animals, feces, secretions, or contaminated fomites
2. In-utero
3. Mechanical

Question 8

What is the hallmark of he disease FPV?

Answer 8

Panleukopenia = destruction of WBC elements

Question 9

In-utero infection of FPV of pregnant queens leads to what?

Answer 9

1. Early fetal death
2. Abortion
3. Mummified births

Question 10

In-utero infection of FPV closer to end of gestation leads to what?

Answer 10

1. Kittens born with varying degrees of neural damage

Question 11

T/F: cerebellar damage form FPV has been commonly reported

Answer 11

True

Question 12

CS of FPV is most commonly seen in what age group of kittens?

Answer 12

3-5 months

Question 13

MLV should not be administer to what 4 animals?

Answer 13

1. Pregnant cats
2. Immunosuppressed cats
3. Sick cats
4. Kittens less than 4 weeks old

Question 14

What is one of the most common infectious disease in dogs?

Answer 14

Canine parvovirus 2 (CPV2)

Question 15

What are the three antigenic variants of CPV2?

Answer 15

CPV2a, CPB2b, CPV2c

Question 16

Which who antigenic variants of CPV2 are seen in N. America?

Answer 16

CPV2b and CPV2c

Question 17

Similar to FPV, CPV2 has what 3 main CS?

Answer 17

1. Enteritis
2. Myocarditis
3. Panleukopenia

Question 18

Enteritis caused by CPV2 leads to what primary CS?

Answer 18

Hemorrhagic diarrhea

Question 19

T/F: serology is the best method to test CPV

Answer 19

False, not the best method bc most dogs have been vaccinated or previously exposed to CPV

Question 20

Due to potential damage by CPV to myocardial or cerebellar cells, which vaccine is preferred in pregnant dogs or colostrum-deprived puppies 6-8 weeks of age?

Answer 20

Inactivated vaccines

Question 21

T/F: oseltamivir can be used in the Tx of canine parvoviral enteritis

Answer 21

True

Question 22

T/F: Porcine parvovirus is an infectious cause of repro failure in swine

Answer 22

True

Question 23

What is the acronym for some of the manifestations of Porcine parvovirus?

Answer 23

SMEDI (stillbirth, mummification, embryonic death, infertility)

Question 24

What is the transmission route of porcine parvovirus (PPV)?

Answer 24

Oronasally in non-immune pregnant sows followed by transplacental transmission (venereal transmission is possible)

Question 25

T/F: death at different stages of pregnancy is typical of PPV infections

Answer 25

True

Question 26

What is a hallmark sign of PPV?

Answer 26

The increase of mummified fetuses after a normal gestation period

Question 27

T/F: abortions are common in PPV infections

Answer 27

False, abortions are uncommon

Question 28

T/F: PPV infections of embryo/fetus (<30days) leads to death and resorption of embryo/fetus, and the dam may return to estrus

Answer 28

True

Question 29

What happens during PPV infection of an early fetus (30-70days)?

Answer 29

Fetuses die and become mummified

Question 30

What happens during PPV infection of late fetus (>70days to term)?

Answer 30

Frequently develop lesions, but also mount an immune response and usually survive in-utero

Question 31

T/F: boars, sows, and gilts usually have inapparent CS or subclinical infections

Answer 31

True

Question 32

T/F: The major cause of SMEDI is porcine parvovirus

Answer 32

True

Question 33

T/F: serologic tests are of good value to Dx PPV

Answer 33

False; they are of limited value bc virus is widespread and vaccination may interfere

Question 34

T/F: PPV can cause persistent infections with periodical shedding of virus

Answer 34

True

Question 35

What is the best way to vaccinate for PPV?

Answer 35

Vaccinate all susceptible breeding stock twice, 2 weeks apart, several weeks before breeding