Path lab slides

Question 1

Answer 1

Benign Prostatic Hyperplasia

Question 1

Answer 1

Ceseating necrotizing granuloma (Mycobacterial TB)

Question 2

Answer 2

Coagulative necrosis in cardiac muscle

Question 3

Answer 3

Forgein body granuloma

Question 4

Answer 4

Forgein body granuloma

Question 5

Answer 5

Hypertrophic scar type 3 collagen deposition in dermis parallel to epidermis

Question 6

describe

Answer 6

Hypertrophic scar type 3 collagen deposition in dermis parallel to epidermis

Question 7

describe

Answer 7

Hypertrophic scar type 3 collagen deposition in dermis parallel to epidermis

Question 8

Answer 8

Hypertrophied cardiac myocytes + enlarged nuclei

Question 9

describe

Answer 9

Keloid Disorganized type 1 collagen deposition in dermis

Question 10

Answer 10

Keloids

Question 11

Answer 11

Liquefactive necrosis (brain)

Question 12

Answer 12

Liquefactive necrosis (brain)

Question 13

Answer 13

Meningioma (Psammoma bodies)

Question 14

Answer 14

Meningioma CT

Question 15

Answer 15

Metastatic calcification (ground glass opacities)

Answer 16

Normal myocardium

Question 17

Answer 17

Diagnosis/Abnormality: Hypertrophic Scar (Parallel Type III collagen fibers); the healing from the scar regresses to within the boundaries, laceration on hand/arm.
Type III collagen deposition in dermis parallel to epidermis.

Question 18

Old man who went gardening bare-foot. Some glass pieces went into his foot, but he has no pain. He says this happened quite a while ago. He came to you because he said it was infected and inflamed. You take the biopsy. Could be a diabetic ulcer, you cut it out – it doesn’t heal all the way properly.

Answer 18

Foreign Body Granuloma

Question 19

Description

Answer 19

Giant cells have central nuclei; foreign bodies are seen in crystalline deposits surrounded by epithelioid macrophages. Langerhans giant cells

Question 20

Description

Answer 20

Mass growing on ear after injury to the site. Biopsy reveals non-parallel/disorganized type I collagen fibers.

Question 21

Double Vision (Diplopia) and headache. MRI will show a ball in the occipital lobe. Blood calcium levels are normal (no affect on calcium)

Answer 21

Meningioma

Question 22

Psammoma bodies  causes necrosis and deposits calcium inside the brain

Answer 22

Meningioma

Question 23

Only tumor that causes dystrophic calcification

Answer 23

Meningioma

Question 24

Patient has known renal failure, diabetic, chest pain, SOB, creatinine is high (indicates kidney poor kidney function) Shows ground glass opacities.

Answer 24

Metastatic calcifications

Question 25

Chronic Renal Failure  Acts on bone and other tissue to release their calcium into the blood, which builds up in different organs. Abnormal bone metabolism high phosphorus and calcium

Answer 25

Metastatic calcification

Question 26

Answer 26

Glands are hyperplastic, papillary-like infoldings with myoepithelial cell layer (small nuclei near BM) What divides the glands from each other? The stroma (purple colour line) There is a double layer of columnar cells (there is normally a single layer) (the cells look normal, but there are just more in number)

Question 27

Old man comes to you dribbling urine

Answer 27

BPH

Question 28

Answer 28

Caseous Necrosis (Cream cheese-y) granuloma; Mycobacterial Tuberculosis

Question 29

Peripheral rim of epithelioid histocytes (Arrows); Caseous material (asterisk) Multinucleated giant cells (triangles) All the way to the left, is the outer rim of lymphocytes and plasma cells. Caseous granuloma  Giant cells nuclei are always peripheral; foreign body granuloma  J cells nuclei are central.

Answer 29

Caseous necrosis

Question 30

Homeless alcoholic comes to you, he has a cavity in his lung, aspiration of food.

Answer 30

Caseous necrosis

Question 31

Answer 31

Liquefactive necrosis; Stroke/Ischemic Stroke/Ischemic Infarction Cell Morphology: Pale areas showing pale infraction, otherwise would be red for haemorrhagic infarction. Loss of neurons and neuroglial cells, clear space seen.

Question 32

Patient comes in with stroke like symptoms, contralateral lesion to where the injury is. CT scan will reveal that the patient had a stroke. Biopsy will be taken and shows the images above. Focal loss of blood supply to the portion of cerebrum.

Answer 32

Liquefactive necrosis

Question 33

Answer 33

Coagulative Necrosis; Neutrophils are seen where the nuclei is supposed to be. Could be secondary to Myocardial infarction

Question 34

Cardiac tissue with normal cardiac muscle architecture. Indicated parts of the tissue are missing nuclei.

Answer 34

Coagulative necrosis

Question 35

Daughter comes to Mother from New Jersey, chest pain she is taking tums for gas, she goes in to management at hospital, she dies. Biopsy is taken but how do we determine when she had the Myocardial Infarction?

Answer 35

2 Weeks ~fibrous tissue 2-3 Days ~ macrophages 2 Days ~ neutrophils (minimum 24hrs) 4-5 Hrs ~ chest pain

Question 36

Answer 36

Hypertrophy, secondary to hypertension.

Question 37

Describe

Answer 37

Cardiac Tissue, ENLARGED Cardiac Myocytes, compared to the normal slide, the cells are enlarged and the nuclei themselves within the cells (myocytes) are enlarged

Question 39

Chest pain, SOB, HTN, and diabetes. Pedal edema. Auscultation shows crackles. X-ray shows pulmonary edema. EKG shows ST elevation. Management in hospital continued  Patient has died. Biopsy of the Patient shows the slide above.

Answer 39

Hypertrophy, secondary to hypertension.

Question 40

Answer 40

Normal cardiac tissue