Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

First Aid MSK, Skin and CT > Pathology 3 > Flashcards

Pathology 3 Flashcards

(72 cards)

Start Studying
1
Q

Progressive symmetrical proximal muscle weakness, endomysial inflammation with CD8+ cells

A

Polymyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Gottron Papules

A

Dermatomyositis, in elbows, knuckles and knees

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Heliotrope (erythematous periorbital) rash

A

Dermatomyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Shawl and Face rash

A

Dermatomyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Anti-Jo-1, anti-SRP, anti-Mi-2 antibodies

A

Dermatomyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Treatment of Dermatomyositis

A

Steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Autoantibodies to post-synaptic ACh-R

A

Myasthenia Gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Worsens with muscle use

A

Myasthenia Gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Improves with muscle use

A

Lambert-Eaton Myasthenic Syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

NMJ disease associated with Thymoma and thymic hyperplasia

A

Myasthenia Gravis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

NMJ disease associated with Small Cell Lung Cancer

A

Lambert-Eaton Myasthenic Syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Autoantibodies to presynaptic Calcium channel

A

Lambert-Eaton Myasthenic Syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Bone in muscle, at site of known trauma or incidental finding

A

Myositis ossificans

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Excessive fibrosis and collagen deposition throughout body. Widespread skin involvement, rapid progressoin, early visceral involvement.

A

Diffuse scleroderma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Limited skin involvement confined to fingers and face.

A

Limited Scleroderma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

CREST syndrome

A

Calcinosis, Raynaud, Esophageal dysmotility, Sclerodactyly, Telangiectasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Anticentromere antibody

A

CREST syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Sclerosis of skin, puffy taut skin with absence of wrinkles. Sclerosis of renal, pulmonary, cardiovascular, and GI systems

A

Scleroderma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Flat lesion with well-circumscribed change in skin color <1cm

A

Macule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Macule >1cm

A

Patch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Elevated Solid lesion <1cm

A

Papule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Papule >1cm

A

Plaque

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Small fluid-containing blister <1cm

A

Vesicle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Large fluid-containing blister >1cm

A

Bulla

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Vesicle containing pus
Pustule
26
Wheal
Hives (uritcaria)
27
Flaking off of stratum corneum
Scale
28
dry exudate
crust
29
Increased thickness of stratum corneum
hyperkeratosis
30
hyperkeratosis with retnetion of nuclei in stratum corneum
parakeratosis
31
Epidermal accumulation of edematous fluid in intercellular spaces
Spongiosis
32
Separation of epidermal cells
Acantholysis (seen in pemphigus vulgaris)
33
Epidermal Hyperplasia (increased spinosum)
Acanthosis Nigricans
34
Normal melanocyte number with decreased melanin production due to decreased tyrosine kinase
Albinism
35
Hyperpigmentation associated with pregnancy or OCP use
Melasma (Choasma)
36
Irregular areas of complete depigmentation caused by destruction of melanocytes
Vitiligo
37
Ephelis
Freckle, normal number of melanocytes, increased melanin production
38
Verrucae
Warts, cauliflower-like papules
39
Pruritic eruption, commonly on skin flexures. Usually starts on the face in infancy and often appear antecubital fossae thereafter
Atopic Dermatitis (Eczema)
40
papules and plaques with silvery scaling esp on knees and elbows
Psoriasis
41
Auspitz Sign
pinpoint bleeding after removing a plaque, Psoriasis
42
Flat, greasy, pigmented squamous epithelial proliferation with keratin-filled cysts (horn cysts)
Seborrheic Keratosis
43
Stuck on lesions
Seborrheic Keratosis
44
Leser-Trelat
sudden appearance of multiple seborrheic keratoses, indicating underlying malignancy. Think carcinoma in GI
45
Very superficial skin infection, usually from S. aureus or S. pyogenes. Honey colored crusting
Impetigo
46
Acute, painful, spreading infection of dermis and subQ tissues, usually from S. pyogenes or S. aureus
Cellulitis
47
Deep tissue injury usually from anaerobic bacteria or S. pyogenes. Results in crepitus from methan and CO2 production
Necrotizing fascitis
48
Exotoxin destroys keratinocyte attachments in the stratum granulosum. Fever and generalized erythematous rash with sloughing of the upper layers of the epidermis that heals completely
Staphylococcal Scalded Skin Syndrome
49
White, painless plaques on the tongue that cannot be scrapped off
Hairy leukoplakia
50
Firm, pink, umbilicated plaques due to poxvirus
Molluscum Contagiosum
51
IgG antibody against desmoglein (desmosome), oral mucosa involved
Pemphigus vulgaris
52
Antibodies around epidermal cells in reticular (net-like) pattern
Pemphigus vulgaris
53
Nikolsky Sign
Separation of epidermis upon manual stroking | Pemphigus vulgaris
54
IgG antibody against hemidesmosome
Bullous Pemphigoid
55
Tense blisters that contain eosinophils
Bullous Pemphigoid
56
IF reveals linear pattern at epidermal-dermal junction
Bullous Pemphigoid
57
IgA at the tips of dermal papillae
Dermatitis herpetiformis
58
Target lesions, necrosis in the center - associated with mycoplasma pneumonia, HSV, sulfa drugs, beta-lactams, phenytoin, cancers and autoimmune disease
Erythema Multiforme
59
Mucosal involvement of the eyes and lips after drug administration
Stevens-Johnson Syndrome
60
Severe form with >30% of the body surface area
Toxic Epidermal Necrolysis
61
Acanthosis nigricans
Hyperpigmented velvety thickening of skin usually neck or axilla associated with hyperinsulinoma and visceral malignancy
62
Premalignant lesions caused by sun exposure. Small, rough, erythematous or brownish papules or plaques.
Actinic keratosis
63
Painful inflammatory lesions of subcutaneous fat, usually on anterior shins
Erythema nodosum
64
Infections that can cause erythema nodosum
sarcoidosis, coccidioidomycosis, histoplasmosis, TB, streptococcal infections, leprosy and Crohn
65
6P's of Lichen Planus
Pruritic, Purple, Polygonal, Planar, Papules and Plaques
66
Wickham striae
reticular white lines, mucosal involvement of lichen planus
67
Sawtooth infiltrate of lymphocytes at dermal-epidermal junction associated with hepatitis C
Lichen Planus
68
Herald Patch
Pityriasis rosea
69
Christmas tree pattern
Pityriasis rosea
70
UVA
Dominant in tanning and photoaging
71
UVB
Sunburn
72
Coolest Irish Cider
Magners

First Aid MSK, Skin and CT (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions