Pathology Flashcards

(43 cards)

1
Q

Rhinitis

A

Rhinovirus, allergic rhinitis, Type I hypersensitivity, eosinophils
Associated with asthma and eczema

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2
Q

Nasal polyp

A

Cystic fibrosis

Aspirin intolerant asthma

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3
Q

Angiofibroma

A

benign tumor in nasal mucosa, epistaxis

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4
Q

Nasopharyngeal carcinoma

A

Malignant
EBV
Pleomorphic keratin-positive epithelial cells

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5
Q

Acute epiglottis

A

H. influenza B

Inspiratory stridor

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6
Q

Laryngotracheobronchitis (CROUP)

A

Upperairway inflammation, parainfluenza

Hoarse barking cough

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7
Q

Vocal cord nodule (singer’s nodule)

A

myxoid, hoarseness, rest voice

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8
Q

laryngeal papilloma

A

Benign, HPV6 and 11

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9
Q

Laryngeal carcinoma

A

squamous cell carcinoma
Risks alcohol and tabacco
hoarseness, cough, stridor

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10
Q

Pneumonia

A

Fever chills, productive cough with yellow-green sputum( pus) or rusty (blood), tachypnea with pleuritic chest pain, decreased breath sounds, dullness to percussion, elevated WBC
Diagnose: CXR, sputum culture, blood culture
three types: lobar pneumonia, bronchopneumonia, interstitial pneumonia

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11
Q

Lobar pneumonia

A

consolidation of entire lobe, S. Pneumoniae, Klebsiella.

Congestion, red hepatization (due to exudate n filling alveolar), gray hepatization (degradation), resolution

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12
Q

Bronchopneumonia

A

scattered pathy consolidation centered around bronchioles, multifocal, bilateral.

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13
Q

Interstitial (atypical) pneumonia

A

Diffuse interstial infiltrates, mild upper resp symptoms (minimum sputum, low fever)
Bacterial or viral

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14
Q

Aspiration pneumonia

A

Alcoholics, comatose patients, Bacteroides, fusobacterium, peptococcus

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15
Q

Tuberculosis (TB)

A
Mycobacterium tuberculosis
Primary TB (asymptomatic) 
Secondary TB (AIDS)
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16
Q

Chronic obstructive pulmonary disease

A

Chronic bronchitis
Emphysema
Asthma
Bronchiectasis

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17
Q

Chronic Bronchitis

A

Blue bloater, Reid index >50%, persistent cough with buckets of mucus

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18
Q

Emphysema

A

Pink puffer, A1AT panacinar w liver cirrhois , smoking centriacinar. Hypoxema, cor pulmonale

19
Q

Asthma

A

TH2, leukotrines, eosinophils, aspirin, spiral-shaped mucus plugs, Charchot-Leyden crystals.

20
Q

Bronchiectasis

A

inflammation, purulent sputum (smelly)

21
Q

Restrictive lung diseases

A

Sarcoidosis, IPF, Pneumoconioses, hypersensitivity pneumonitis

22
Q

Idiopathy pulmonary fibrosis

A

TGF beta, bleomycin, amiodaone, honeycomb lung, transplantation

23
Q

Pneumoconioses

A

Asbestosis, Berylliosis, Coal miners pneumoconiosis, Silicosis

24
Q

Asbestosis

A

Lung cancer, mesothelioma,, pleural plaques, asbestos bodies

25
Silicosis
Fibrotic nodules in upper lobes of lungs, TB risk increases
26
Coal Miners pneumoconiosis
Caplan syndrome, anthracosis, Rheumatoid arthitis, black lung
27
Berylliosis
Aerospace, noncaseated granuloma, risk lung cancer | Tx: corticosteroids
28
Sarcoidosis
Elevated ACE, Hypercalcemia, asteroid bodies, AA females, noncaseating granulomas, Tx: Steroids or goes away
29
Hypersensitivity pneumonitis
Pigeon breeder's lung, granulomatous, fever, flu-like symptoms
30
Pulmonary Hypertension
>25 mmHg, primary (BMPR2) and secondary
31
Respiratory Distress syndrome
whiteout, hyaline membrane, give PEEP
32
Neonatal respiratory distress syndrome
hyaline, low surfactant (lecithin/ DPPC) | Norm ratio >2
33
Small cell carcinoma
Chemo, smoking, central, syndromes
34
Squamous cell carcinoma
Keratin pearls, male smoker, central PTHrP
35
Adenocarcinoma
Most common, nonsmokers, female smokers, glands mucin, pleural involvement
36
Large cell carcinoma
poorly differentiated, smoking, central or peripheral, poor prognosis
37
Bronchioloalveolar carcinoma
Not related to smoking, peripheral, Pneumonia-like
38
Carcinoid tumor
Not related to smoking, central or peripheral . low-grade malignancy
39
Metastasis to the lung
From breast and colon
40
Pneumothorax
spontaneous or tension
41
Spontaneous pneumothorax
trachea side of collapse
42
Tension pneumothorax
trachea opposite side, MEDICAL EMERGENCY
43
Mesothelioma
Exposure to asbestos, malignant neoplasm | Presents: Recurrent pleural effusions, dyspnea, and chest pain; Tumor encases the lung