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Flashcards in Pathology Historology Deck (28):
1

Abnormal azurophilic primary granules

Toxic granules - Sepsis (severe infection)

2

Patches of dilated ER that appear as sky-blue cytoplasmic puddles

Dohle bodies - Severe infection

3

Distinctive needle like azurophilic granules found in myeloblasts

Auer rods - AML, NHL, Thyroid cancer

4

Scarrered macrophages with abdundant wrinkled greenblue cytoplasm

Sea-blue histiocytes - CML

5

Small lymphocytes disrupted in the process of making smears

Smudge cells - CLL

6

Large cells with multiple nuclei or a single nucleus with multiple nuclear lobes

Reed Sternberg cells - Hodgkin cell

7

Nuclear remnants are phagocytosed by interspersed cells with abundant clear cytoplasm or lipid droplets

Starry sky pattern - Burkitts lymphoma

8

Cells found in adult Tcell lymphoma which appear to have multilobulated nuclei

Cloverleaf or flower cells - Adults t-cell lymphoma

9

Destructive plasma cell tumors involving axial skeleton

Plasmocytoma - Multiple myeloma

10

Multiple nuclei, prominent nuclei, and cytoplasmic droplets containing Ig

Bizzare multinucleated cells - multiple myeloma

11

Fiery red cytoplasm

Flame cells - Multiple myeloma

12

Pink cytoplasmic inclusions

Russell Bodies - Multiple myeloma

13

Blue globular nuclear inclusions

Dutcher bodies - Multiple myeloma

14

M proteins causes RBCs in PBS to stick in linear arrays

Rouleaux condormation - Multiple myeloma

15

Erythroblasts with ironladen mitochondria visible as perinuclear granules

Ringed Sideroblasts - Sideroblastic anemia, INH, Lead, copper poisoning, Multiple myeloma, RA, B6 deficiency

16

Neutrophils with only two nuclear lobes

Pseudo-pelger Huet cells - MDS

17

Megakaryocytes with single nuclear lobes or multiple separate nuclei

Pawn ball megakaryocytes - MDS

18

Premature release of nucleated erythroid and early granulocyte progenitors

Leukoerythroblastosis - Primary myelofibrosis

19

Cells that were probably damaged during the birthing process in the fibrotic marrow

Tear drop cells or dacryocytes - Primary myelofibrosis

20

Pentalaminar tubules often with a dilated terminal end or tennis racket like appearance

Birbeck granules - Langerhans cell histiocytosis

21

Small yellowbrown, brown or rustcolored foci in the spleen

Gandy gamma nodules - Splenic congestion

22

Small hyperchromic RBC lacking central pallor

23

Small dark nuclear remnants present in RBCs of asplenic patients

Howell Jolly bodies

24

Membrane bound precipitates on denatured globin chains

Bite cells - G6PD

25

RBCs shaped like curved blades

Sickle cells - Sickle cell anemia

26

Dehydrated cells with bulls eye appearance

Target cells - B thalassemia, sickle cell anemia

27

Fragmented RBCs called helmet cells if cut in half

Schistocytes - RBC trauma, DIC, HUS, TTP

28

RBCS with spikes

Burr cells or echinocytes - Valve replacements, RBC trauma