Pathophys Gastroparesis Flashcards Preview

GI & Liver Fall 2013 CBD > Pathophys Gastroparesis > Flashcards

Flashcards in Pathophys Gastroparesis Deck (11):
1

2 major Functional areas of stomach & functions

fundus (relaxation/acommodation)
antrum/body (grinding/mixing/transfer)

2

where's the pacemaker

mid part of greater curvature

3

fundic abnormality result

can't get food in

4

antral or pacemaker abnormality result

can't get food out

5

causes of gastroperesis

diabetes (30%)
idiopathic (30%)
post-surg (15%)
viral (8%)
misc/parkinson's/pseudo-obstruction/sclerdermer

6

symptoms of gastroparesis

nausea (93%)
abdominal pain (90%)
early satiety/anorexia (86%)
vomiting (68%)

7

dx of gastroparesis

history & exam
labs
need upper endoscopy
gastric emptying study
rarely electrogastrograhy

8

alternative to endoscopy in gastroparesis

barium swallow

9

gastric emptying study

>10% at 4 hrs is indicative of delayed gastric emptying

10

principles of management of gastroparesis

general supportive care
decompression (peg tube)
suppression of bacterial growth
symptomatic tx of diarrhea/constipation
nutrition

11

medical tx for gastroparesis

anti-emetics (phenargan & ondanstron)
metoclopramide (bbw tremmors)
macrolide antibiotics (mimic motolin)
cisapride (stim 5HT4 receptors, banned)
domperidone (bought in CA)
botox
gastric pacemaker