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Flashcards in Pediatrics 7/8 Deck (13):
1

2 nephrogenic forms of hypertention

1. Renin Mediated
2. Volume overload

2

Normal GFR in preterm/term baby

Preterm: 15 ml/mon/1.73m2
Term: 20 ml/min/1.73 m2

3

What defines normotensive in kids

>90%ile for sex/age/length

4

Ford's Four

Kidney Function (filtration/tubular activity)
Blood pressure
Urine (blood/protein?)
Anatomy (i.e. ultrasound)

5

Types of proteinuria in kids

- Transient
- Orthostatic: not persistent; leak protein when up on feet, etc
- Persistent: what we worry about; check a 1st morning void r/p transient

6

Nephrotic Syndrome characteristics

1. Nephrotic range proteinuria (Upr:cr >2)---HAVE TO HAVE
2. Low serum albumin
3. Edema
4. High Serum cholesterol---should be high with MCD. If nl, have lymphoma, lupus

7

Hematuria

5-10 RBCs /hpf on 3 separate checks

need to confirm with U/A with micro

8

Nephritis

1. RBC casts on microscopic urine!!!
2. Edema
3. Hypertension
4; Acute kidney injury
- CHECK C3

9

Basic physiology of nephrotic syndrome

Glomeruli are leaky; intravascular volume depleted

Diuretics contraindicated

10

Basic physiology of nephritis

Gloms are inflammed, so volume overloaded/hypertensive

Diuretics indicated
Edema caused by increase in hydrostatic pressure

11

Low C3 indicates...

Acute Post-infectious GN:
- C3 normalizes in 4-6 weeks
Lupus
- C3 corresponds with lupus flairs
Membranoproliferative
- C3 remains low (hypocomplementemic GN)
- treat with 2 years on steroids

12

Most common nephritis?

IgA Nephropathy

13

Renal Tubular Acidosis

Non-gap metabolic acidosis without diarrhea (

3 types
Type I: distal; can't acidify urine; RARE
Type II: most common; proximal tubule; can't reabsorb enough bicarb but grow out of it; compensate with more bicarb
Type III: mixed