Penicillin

Question 1

Natural penicillins

Answer 1

• Penicillin G
• Penicillin V

Question 2

Antistaphylococcal penicillins

Answer 2

• Methicillin
• Cloxacillin, dicloxacillin
• Nafcillin
• Oxacillin

Question 3

Aminopenicillins

Answer 3

• Ampicillin
• Amoxicillin

Question 4

Antipseudomonal penicillin

Answer 4

Carboxypenicillins – Carbenicillin, Ticarcillin

Ureidopenicillins – Piperacillin, Mezlocillin

Question 5

Gram (+) cocci

Answer 5

• Streptococcus pneumoniae*
• Streptococcus pyogenes
• Viridans streptococci* group

Question 6

Gram (+) bacilli

Answer 6

Bacillus anthracis
* Corynebacterium diphtheriae

Question 7

Gram (-) cocci

Answer 7

Neisseria gonorrhoeae
* Neisseria meningitidis

Question 8

Spirochetes

Answer 8

Treponema pallidum
* Treponema pertenue

Question 9

Anaerobic organism

Answer 9

Clostridium perfringens

Question 10

Antistaphylococcal penicillins

Answer 10

Methicillin (no longer used)
Oxacillin, Cloxacillin,Dicloxacillin
Nafcillin

Question 11

Combination of penicillin with
B-lactamase inhibitors

Answer 11

a. Amoxicillin + clavulanic acid (po, i.v.)

b. Ampicillin + sulbactam (i.v., i.m.)

c. Piperacillin + tazobactam (i.v.)

Question 12

Treatment of penicillin induced hypersensitivity reactions

Answer 12

Adrenaline 0.3–0.5 mL of 1:1000 solution (1 mg/mL) IM
* Inj. hydrocortisone 100–200 mg intravenously
* Inj. pheniramine 45 mg intramuscularly/intravenously
* Intravenous fluids