Pentose Phosphate Pathway Flashcards Preview

5242 Cell Metabolism 2 > Pentose Phosphate Pathway > Flashcards

Flashcards in Pentose Phosphate Pathway Deck (7)
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1

Where does the pentose pathway occur in the cell? What type of cells?

In the cytosol. In liver cells.

2

The oxidative branch of the PPP is also called?

The hexose monophospate shunt

3

Where does the Oxidative branch of PPP occur in the glycolysis pathway? What enzyme is used and what is mainly produced? Reversible?

At Glucose 6-P. Glucose 6-P Dehydrogenase. Produces 2 NADPH, 1 CO2 and 3 Ribose-5P. Irreversible.

4

What is Glucose 6-P Dehydrogenase inhibited by?

NADPH

5

What is NADPH also involved in? Helps regenerate what?

it is used in the reduction of reactive oxygen species. Used to regenerate Glutathione.

6

What is the most common human deficient enzyme?

G6PDH

7

Where does the non-oxidative branch of PPP start on the Glycolysis pathway? What does it produce? Reversible?

The Fructose 6-P, and splitting phase of GA-3P. Produces 3 Ribose-5P. Reversible.