Peripheral Nerve Diseases Flashcards
A patient explains that she felt like she had the flu, but soon both of her legs were slightly numb and she was unable to move them. She has no reflexes.
What is the mechanism of pathology?
Immune mediated demyelination of peripheral nerves
A patient explains that she felt like she had the flu, but soon both of her legs were slightly numb and she was unable to move them. She has no reflexes.
What is the diagnosis?
Guillain-Barre syndrome
A patient explains that she felt like she had the flu, but soon both of her legs were slightly numb and she was unable to move them. She has no reflexes.
What do you need to watch out for? What is the treatment?
Dangerous if reaches respiratory center. Usually resolves itself.
What is the causative organism of leprosy? The mode of transmission?
Mycobacterium leprae, respiratory droplet
What histological observation can be made when looking for mycobacterium leprae?
Granulomas. the bacterium can only be found with acid fast stain
The form of leprosy which is much less problematic is called…
Tuberculoid leprosy
What happens to nerves with M. leprae?
they degenerate, resulting in anesthesia, ulcers, contractures
The more severe form of leprosy is called…
Lepromatous leprosy
Lepromatous leprosy is more severe because…
T cells arent as strong, granulomas dont form
What immune response cell can be observed in a herpes zoster section?
Multinucleated giant cell
Charcot-Marie-Tooth disease results from…
Repetitive demyelination and remyelination
What are the functional problems with CharcotMT disease…
muscle loss, loss of sensation, but still has pain
