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Flashcards in Brain Neurotransmitter Systems Deck (19)
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0

Hyperpolarization usually involves what kind of receptors?

G-protein

1

Of inhibitory or excitatory, which signal is more prominent?

Inhibitory (90%)

2

What does lidocaine do?

Blocks sodium channels and prevents signal propagation

3

What does DOPA do and what is it used to treat?

DOPA is an intermediate product between tyrosine and dopamine, it is used to treat Parkinsons

4

What does reserpine do?

Depletes neurotransmitter stores, specifically norepinephrine

5

What do monamine oxidase inhibitors do?

Prevent metabolism of neurotransmitters

6

What does methamphetamine do?

Increases release of neurotransmitters

7

What does cocaine do?

Prevents dopamine reuptake into presynaptic terminals

8

Pathways that are aligned linearly for sensory perception or motor control are called...

Hierarchical systems

9

Neurological systems that spread out and do not follow a direct path are called

diffuse systems

10

What types of neurotransmitters are found in hierarchical systems?

Glutamate, GABA, glycine

11

What types of neurotransmitters are associated with diffuse systems?

acetylcholine
dopamine
norepinephrine
serotonin
cannabinoids
opiates

12

What are the three types of receptors for glutamate?

NMDA (Ca, Na and K), AMPA (Na & K), Kainic acid (Na &K)

13

Does GABA inhibit or excite postsynaptic neurons?

inhibit

14

Does glutamate inhibit or excite presynaptic neurons?

inhibit

15

What is the difference between GABAa and GABAb?

GABAa is a chloride channel, GABAb is a metabotropic receptor that augments K channels and inhibits Ca channels

16

What is glycine? Inhibitory or excitatory?

inhibitory

17

Which dopamine receptor is defective in Parkinson's disease?

D2

18

Bipolar disorder and schizophrenia are associated with what kind of receptor?

5HT2a receptors (serotinin receptors)