Pharm Exam III Numbers Flashcards
All answers are numbers (74 cards)
1
Q
How much more is CO2 diffusable than O2?
A
20x
2
Q
How quickly will N2O diffuse into the air-filled cavity?
A
10 L in 10-15 minutes
3
Q
Blood:Gas Partition Coefficients: Halothane
A
2.54
4
Q
Blood:Gas Partition Coefficients: N2O
A
0.46
5
Q
Blood:Gas Partition Coefficients: Desflurane
A
0.42
6
Q
Blood:Gas Partition Coefficients: Isoflurane
A
1.46
7
Q
Blood:Gas Partition Coefficients: Sevoflurane
A
0.69
8
Q
MACawake
A
0.3-0.5
9
Q
MACBAR
A
1.7-2.0 MAC
10
Q
MAC: N2O
A
104
11
Q
MAC: Halothane
A
0.75
12
Q
MAC: Isoflurane
A
1.17
13
Q
MAC: Desflurane
A
6.6
14
Q
MAC: Sevoflurane
A
1.8
15
Q
MAC Age: 55-60
A
-6% per decade
16
Q
MAC Age: 30-55
A
+/- 0%
17
Q
MAC Age: 10s
A
+12%
18
Q
MAC Age: peak
A
1 year old
19
Q
MAC Age: 20s
A
+6%
20
Q
MAC Age: 70s
A
-12%
21
Q
No change in MAC: PaCO2
A
15-95 mmHg
22
Q
No change in MAC: PaO2
A
> 38 mmHg
23
Q
Vapor Pressure: Halothane
A
243 mmHg
24
Q
Vapor Pressure: Isoflurane
A
238 mmHg
25
Vapor Pressure: Desflurane
669 mmHg
26
Vapor Pressure: Sevoflurane
157 mmHg
27
MAC: Burst Supression
1.5 MAC
28
MAC: Electrical Silence (Brain Death)
2 MAC
29
MAC: Dose related decrease in amplitude and increase in latency for both SSEP and MEP
0.5-1.5 MAC
30
Autoregulation of CBF
60-160 mmHg
31
MAC Loss of Autoregulation CBF: Halothane
0.5 MAC
32
MAC of Autoregulation CBF: Sevoflurane
1 MAC
33
MAC Loss of Autoregulation CBF: Isoflurane & Desflurane
0.5-1.5 MAC
34
MAC: Increased ICP
Onset > 0.8 MAC
35
Amount increase in ICP by anesthesia
7 mmHg
36
MAC: Apnea
1.5-2.0 MAC
37
MAC: Blunt hypoxic response (COPD)
50-70% depression: 0.1 MAC
100% depression: 1.1 MAC
38
MAC: Hypoxic Pulmonary Vasoconstriction
50% depression at 2 MAC
39
MAC: Sevo increases HR
> 1.5 MAC
40
Hepatotoxicity: Type I
1-2 weeks after exposure
20% of patients
41
Hepatotoxicity: Type II
1 month after exposure
42
MAC: Increased portal vein flow
1-1.5 MAC
43
MAC: N2O vomiting
> 0.5 MAC
44
MAC: Obstetric Effects
0.5-1.0 MAC
45
1 Hz: Seconds
1 second
46
TOFR: Amplitude of 4th twitch is 50% of the 1st
0.5
47
TOFR: Experienced anesthetists' unable to detect fade
> 0.4
48
TOFR: Significant residual
0.7-0.9
49
50
Bedside extubation criteria..
PIP = 25-30 cmH2O
51
Succinylcholine: Dose
1 mg/kg
52
Succinylcholine: Onset
30-60 seconds
53
Succinylcholine: Duration
3-5 minutes
54
Succinylcholine: K+ leak
0.5 mEq/L
55
TOFR: Phase I Block
> 0.7
56
Succinylcholine: Overdose
2-4 mg/kg
57
Succinylcholine: duration if dibucaine number is 20
3 hours (normal dose)
58
Succinylcholine: Increased intraocular pressure
Maximum increase 2-4 minutes after administration
Lasts 5-10 minutes (transient)
59
Fasciculation dose of non-depolarizing NMBD
1/10th of Vec or Roc dose
60
Dantrolene: Dose
2.0 mg/kg; max 10mg/kg
61
MAC: Ischemic Preconditioning
0.25 MAC
62
What is the temperature in the OR?
20-22o
63
What is the temperature in the absorber?
40-60o
64
How much moisture is in soda lime?
15%
65
NIOSH limits for potent anesthetics
2ppm; 25ppm for N2O
66
How long will it take for the brain to equalize with the spinal cord?
10-15 minutes
67
N2O reduces MAC by...
1% for each % of N2O
68
MAC decreases by 50% for each...
10o decrease in temperature
69
Tetanic stimulation
50 hz for 5 seconds
70
Post-tetanic stimulation
1 twitch 3 seconds after stimulation
71
Synaptic Cleft
20-50 nm wide
72
Ready Release Vesicles
5,000-10,000
73
Pentameric unit
5 sub pores
74
Succinylcholine: MG Dose
1.5-2mg/kg
