Pharm- NSAIDs Flashcards Preview

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Flashcards in Pharm- NSAIDs Deck (21):
1

Naproxin- Indications

Less CV activity than other NSAIDs

2

Naproxin- MOA

COX inhibitor- reduces prostaglandin & thromboxane

3

Naproxin- AE

GI bleeding, ulcer, dyspepsia

4

Naproxin- Dosing

250-500 mg q 12h for antiinflammation. Don't exceed 1250 mg/day

5

Aspirin- Indication

Original NSAID, more commonly used for CV now

6

Aspirin- MOA

Anti platelet (irreversible binding to platelets), COX inhibitor, antipyretic.

7

Aspirin- AE

Reyes syndrome, GI bleeds, rashes, toxicity

8

Celebrex- Indications

Patients at high risk for GI bleeds, NSAID intolerance,

9

Celebrex- MOA

Selective COX 2 inhibitor

10

Celebrex- AE

CV & GI side effects, anemia

11

Ibuprofen- Indications

Pain & inflammation

12

Ibuprofen- MOA

COX inhibitor

13

Ibuprofen- AE

GI & CV

14

Indomethacin- Indications

Bursitis, OA, tendonitis

15

Indomethacin- MOA

NSAID- COX inhibitor

16

Indomethacin- AE

Lower risk of CV events than others, higher GI

17

Meloxicam- Indications

OA, RA

18

Meloxicam- MOA

NSAID- Cox inhibitor, increased COX 2 inhibition

19

Ketorolac- Indications

Pain- severe to moderate

20

Ketorolac- MOA

Increased COX 2 inhibitor

21

Ketorolac- AE

GI