Pharm- Opiods Flashcards Preview

SMB 4 > Pharm- Opiods > Flashcards

Flashcards in Pharm- Opiods Deck (24):
1

Morphine- Indications

Severe pain, gold standard opiate.

2

Morphine- MOA

Blocks substance P, alters perception of pain, centrally acting

3

Morphine- AE

Constipation, respiratory depression

4

Hydromorphone- Indication

Severe pain! Better for patients with renal impairment

5

Hydromorphone-MOA

Inhibits substance P, binds to opioid receptors

6

Hydromorphone-AE

constipation, resp. depression, addiction

7

Tylenol with Codeine- Indications

Moderate to severe pain, antitussive

8

Tylenol with Codeine- MOA

Acetaminophen- inhibits prostaglandin synthesis, pain impulse
Codeine- Binds to opiate receptors, inhibits ascending pain pathway, suppresses cough

9

Tylenol with Codeine- AE

Resp. depression, dizziness, caution in renal & hepatic impairment

10

Hydrocodone- Indications

Moderate to severe pain

11

Hydrocodone- MOA

Converted to morphine in liver- blocks opioid receptors.

12

Hydrocodone- AE

CNS depression, constipation

13

Oxycodone- Indications

Moderate to severe pain

14

Oxycodone- MOA

Semisynthetic derivative of morphine

15

Oxycodone- AE

Resp depression, constipation, increased intracranial pressure

16

Meperidine- Indications

Acute pain, short term use

17

Meperidine- MOA

Binds to Mu receptors, different than morphine. Synthetic

18

Meperidine- AE

Anxiety, tremors, muscle twitch, lower seizure threshold

19

Methadone- Indications

Chronic pain management, withdrawal from opioids due to long life

20

Methadone- MOA

Strong agonis- binds to mu and NMDA receptor increasing duration of effects.

21

Methadone- AE

Euphoria, hypotension, liver & renal failure

22

Tramadol- Indications

Mild & neuropathic pain

23

Tramadol- MOA

Weak agonist, inhibits uptake of neurotransmitters, CNS inhibition

24

Tramadol- AE

Seizures, anxiety, N/V, sedation