Pharm Questions Flashcards Preview

MSK > Pharm Questions > Flashcards

Flashcards in Pharm Questions Deck (18):
1

SE: rash, Stevens-Johnson Syndrome, hypersensitivity syndrome, bone marrow suppression

Allopurinol

2

Dx-dx: increase opioids, benzos, hypotensives, increases toxicity of ethanol, CNS depressant, TCAs, CLINDAMYCIN

Baclofen

3

SE anticholinergic effects, inhibits SSRI, xerostomia, dizziness

cyclobenzaprine

4

Black Box warning: TB, malignancy, infection

Tofacitinib (xeljanx)

5

SE:
arachnoiditis
subacute toxicity rxn (motor paralysis, CN palsey, seizure, coma)
pulmonary fiborsis
hepatotoxicity
bone marrow suppression
Stevens-Johnson syndrome

Methotrexate

6

Indications:
1. RA
2. ulcerative colitis
3. off-label Crohns Disease
4. psoriasis
5. psoriatic arthritis

Sulfasalazine

7

MOA: inhibition of cytokines and inflammatory mediators

prednisone

8

MOA: Inhibits leukocyte migration, phagocytic activity

colchine

9

Anticholingeric SE (urinary retention, tachycardia, hypotension)

sedation

amitryptiline

10

Contra:
1. severe hepatic impairment (Child-Pugh score over 10)
2. severe asthma
3. closed glaucoma
4. CV disease
5. biliary tract disease
6. COPD

Pilocarpine

11

Dx-Dx:
1. MAOIs
2. sedating drugs
3. SSRIs

tramadol

12

rash with first infusion

Rituximab

13

naturally occuring agonist of IL-1 receptor which reduces degradation of cartilage

Anakinra

14

dx-dx:
1. anti-coags
2. NSAIDs
3. diuretics
4. lithium
5. anti-HTN meds

ibuprofen

15

Indications:
1. RA
2. leukemias
3. breast cancer
4. lymphomas
5. myeloma
6/ corticoid refractory nephrotic syndrome

Cyclophosphamide

16

reversible infertility in men

sulfasalazine

17

counteracted by low dose ASA

probenacid

18

possible rash with ampicillin/amoxicillin

allopurinol