Pharmacogenomics Flashcards Preview

Pharmacology Pt. 2 > Pharmacogenomics > Flashcards

Flashcards in Pharmacogenomics Deck (4)
Loading flashcards...
1

Name the three genetic variants that predict response of an individuals pharmacokinetics and dynamics.

Enzymes, transporters, receptors.

2

When administering a drug that contains genetic information on the label, are clinicians required to perform genetic tests prior to administration?

No

3

The two single nucleotide polymorphisms that can have an effect on how warfarin functions are _____ and _____.

CYP2C19 and VKORC1 (vitamin K dependent epoxide reductase).

4

People who have diminished ______ enzyme activity would be less likely to experience a therapeutic response to the prodrug Clopidogrel.

CYP2C19