Pharmacologic Mngmt Part II Flashcards
When should pain be evaluated and documented?
At each appointment
Examples of non-opioid analgesics
NSAIDs
Acetaminophen
First-line therapy for pre and post-op procedures
Non-opioid analgesics
Cause respiratory depression.
Opioid analgesics.
Ibuprofen (NSAID) brand name
Motrin or advil
Ibuprofen dose for children under 12.
4-10 mg/kg every 6-8 hrs
Ibuprofen dose for children > 12, and adults
200 mg every 4-6 hrs
Inhibit the Cylcooxygenase conversion of arachidonic acid to prostaglandins
NSAIDs
What is Reye’s Syndrome
Brain, liver, and kidney damage caused by aspirin use in children
Caution with NSAID’s
GI disease, bleeding conditions, impaired renal function
Analgesic, anti-pyretic, and anti-inflammatory.
NSAIDs
Brand name of Acetaminophen
Tylenol
Does NOT have anti-inflammatory properties.
Acetaminophen
Acetaminophen dose in kids under 12
10-15 mg/kg every 4-6 hrs
Acetaminophen dose in kids > 12
325-650 mg every 4-6 hrs
Overdose of Acetaminophen can cause what?
Acute liver failure
Acetaminophen is metabolized into this toxic intermediate.
NAPQ1
Detoxifies NAPQ1
Glutathione
Acetaminophen is broken down to ______, which is broken down by ______.
NAPQ1, Glutathione
Initial symptoms of Acetaminophen toxicity.
Nausea, vomiting, drowsiness, lethargy, malaise
Acetaminophen toxicity symptoms progress to:
Upper right quadrant pain, Tachycardia, hypotension, hepatic dysfunction, multi-organ failure.
Antidote for Acetaminophen toxicity, that increases Glutathione levels
NAC (N-acetylcysteine)
Liquid Acetaminophen with Codeine contains what?
120 mg of Acetaminophen + 12 mg Codeine/5 mL suspension
Tablet form of Acetaminophen + Codeine contains what?
Tablet #2
Tablet #3
Tablet #4
Tablet #2 = 300 mg aceta + 15 mg codeine
Tablet #3 = 300 mg aceta + 30 mg codeine
Tablet #4 = 300 mg aceta + 60 mg codeine