Pharmacology - 1 Flashcards Preview

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Flashcards in Pharmacology - 1 Deck (9)
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1

Define drug 

A chemical entity used to prevent or alter the course of a disease. 

2

What are the two main types of drugs?

Small molecules 

Biologics 

3

Small molecules are usually very small, often just a few atoms. Biologics are huge in comparison 

Comparing the size of small molecule and biologics 

4

What are the targets of drugs?

  • Targets that are involved a particular disease process
  • Then exhibit the required response 

5

Define drug target and give examples 

A macromolecular component of a cell with which a drug interacts to produce a response. They are usually proteins 

6

How do drugs work? 

  • Most drugs act on receptors, these can be inside the cell or more commonly on the cell surface 
    • Must form a tight bond with the receptor 

7

Drugs can either stimulate or inhibit a receptor. What names are given to this? 

 

Agonist 

Antagonst 

8

Common drug targets 

 

  • Enzyme linked receptors 
  • ion channel linked 
  • G protein linked 
  • Nucelar receptor (usually much longer lasting) 

9

Describe Bisoprolol