Pharmacology

Question 1

Movement of the body on the drug

Answer 1

Pharmacokinetics

Question 2

Effect of the drug on the body

Answer 2

Pharmacodynamics

Question 2

Principal Phases in Pharmacokinetics

Answer 2

Absorption
Distribution
Metabolism
Excretion & Elimination

Question 3

Percentage of dose going thru systemic circulation

Answer 3

Absorption

Question 4

Drug percentage absorbed

Answer 4

Bioavailability

Question 5

First pass effect

Answer 5

Absorbed in the small intestine –> Directed to liver for metabolism

Question 6

Movement of drug from systemic circulation to tissues & organs

Answer 6

Distribution

Question 7

Volume of DIstribution

Answer 7

Amount of Drug Absorbed + Concentration of Drug in the Plasma

Question 8

Chemical changes in the drug after administration

Answer 8

Biotransformation

Question 9

Primary site for Drug Metabolism

Answer 9

Liver

Question 10

Other Systems for Drug Metabolism

Answer 10

Lungs
Stomach
Kidneys
Skin

Question 11

Primary site for Drug Excretion

Answer 11

Kidneys

Question 12

Organs and tissue ability to clear the drug effect out of the system

Answer 12

Clearance

Question 13

Amount of time required for 50% of the drug remaining in the body to be eliminated

Answer 13

Half-life

Question 14

Binds to a receptor and produces intracellular reaction

Answer 14

Agonist

Question 15

Blocks receptor sites; reduces actions of agonist

Answer 15

Antagonist

Question 16

Produces submaximal reaction

Answer 16

Partial Agonist

Question 17

Inhibits normal functioning of cells

Answer 17

Inverse Agonist