Pharmacology Flashcards

(53 cards)

1
Q

drugs that end with the suffix prazol are:

A

PPI

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2
Q

ppi are usually take ____ and. they work on ______
DOA
MOA

A

empty stomach
k/h pump

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3
Q

PPI side effects

A

vit.b12 , iron, calcium, magnisium deficiency
osteoperosis
diarrhea
infection ( c difficle)

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4
Q

The drug that has a DDI with PPI and what are the substitute

A

clopidogrel
rabeprazol, pentaprazol

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5
Q

drugs that end with the suffix : tidine are

A

H2 blockers

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6
Q

rantidine is used iv cus _____

A

iv infusion
histamine > bradycardia and hypotention

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7
Q

side effects of H2 blockers and which is the most seen in:

A

cimetidine

androgenic effects
CNS
liver enzymes

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8
Q

should u stop ppi and h2 blocker fast?

A

no

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9
Q

the ppi and h2 combo is used for

A

all ulcers

GERD
zollinger ellison syndrome

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10
Q

What does sucralfate compose of and whats the best ph for it
what is it and whats the side effects

A

sucralfate of Al and salts
Low ph
constipation and renal failure

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11
Q

cant be used with ppi and h2 blocker

A

sucralfate

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12
Q

colloidal bismuth compund
side effects

A

black
anti diarrhea

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13
Q

the PGE2 analoge that is used for NSAIDS ____
and its side effects

A

misoprostol

pregnancy

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14
Q

magnisium hydroxide side effects:
alaminum hydroxide side effect:

A

diarrhea
consitpation

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15
Q

simethiocone ______

A

is a anti gas drug used with antacids

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16
Q

alginic acids is a_____

A

anti reflux used on antacids

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17
Q

triad therapy of peptic ulcer

A

2 weeks

amoxicillin
clarithromycin
ppi

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18
Q

quadruple therapy of peptic ulcer

A

ppi
metronidazole
tetracyclin
bisthmus

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19
Q

ondansterone and granisterone
are _____ antagonist used as an antiemetic

A

Seratonin antagonist
5 HT3

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20
Q

odansterone and granisterone ROA
and uses

A

orally and parentrally
chemotherapy and readiotherapy
for its effecay and long DOA

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21
Q

Metoclopramide and dompiradone are

A

dopamine antagonist

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22
Q

a dopamine antagonist thats :
1. cross the BBB
2. pro kinetic
3.contraindicated for children
4. s/e: parkinosism and extrapyramidal and hyperprolactinema
5. used for: endoscopy and emergencies

A

dopamine antagonist Metoclopramide

23
Q

the dopamine antagonist domperidone
BBB:
childre:
side effects:
uses:

A

doesnt cross
DOC
hyperprolcatinemai and qt elongation
morning sickness

24
Q

pro kinetics (dopamine antagonist) can ___ the tone of LES

25
dopamine antiemetics are used for:
drug induced vomitting radiotherapy and chemotherapy post operation GERD DIABETIC GASTROPARESIS
26
M1 drug thats antiemitic and uses of it :
scopalmine behind ear patches prophylactic 2h
27
H1 blockers that are used for vomiting, what are their indications
Morning sickness Prevention of motion, sickness Motion, sickness, treatment
28
Dexamethasone, Methylprednisone are. both _______ and used for
Glucocorticosteroids used combined prevention of acute vomiting
29
pyridoxine is sued as antiemetic for
preganacy morning sickness
30
cannabinoids are used as antiemetics for what :
severe vomiiting used combined
31
Neurokinin receptor (NK-1) blockers are used for
chemotherapy combined
32
we use _____ for motion sickness
M1 and H1
33
____ used for morning sickness
B6 D2 H1
34
drug induced vomiting we use_____
D2
35
Post operation vomiting, we use___
all but cann, B6, cortico
36
GERD we use___ of antiemetics
D2
37
Diaberic gastroperisis we use
D2
38
endoscopy we use
D2
39
Chemotherapy we use
all but B6 H1 M1
40
Radiotherapy we use _____ antiemetics
5 HT3 D2 cann
41
absorbant agents that are antidiarrheal
aluminum hydroxide and charcoal
42
antisecretory agents used as anti diarrheals
Bismuth subsalicylate
43
Anti-motility agents :
■ Antimuscarinic ■ Diphenoxylate ■ Loperamide no BBB = no addiction
44
Irinotecan (cancer chemotherapy), early form of vomitting is treated with______, late form is treated with________, in severe we use_______
Atrophine loperamide atrophime with diphenoxylate
45
caster oil is considered and not used with
irritant pregnant women
46
bran is considered a
bulk forming physical purgatives laxatives
47
mg sulfates lactulose polyethylene glycol area all
saline and osmotic laxatives that are physical
48
_____ is used with hepatic enchepalopathy
lactulose
49
glycerine supp are:
lubricants stool softener
50
docusate sodium is a
surfactant stool softener
51
Lubiprostone is a ______ and used for____
chloride channel activator used for IBS with costipation
52
——- used as combination with antibiotics to deal with pylori
Ppi and bisthmus
53
Atrophine is an ———
Antimuscarinic